Mesenchymal Stem Cell-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Ameliorate Diabetic Polyneuropathy in Mice
Figure 5
Distribution of the transplanted mesenchymal stem cell (MSC)-like cells. (a) The transplanted MSC-like cells expressing GFP (inset) engrafted in a soleus muscle (upper panels). Lower panels are magnified images of insets. Scale bar = 50 μm. IB4: isolectin GS-IB4. (b) In a soleus muscle, the MSC-like cells engrafted in one of the peripheral nerve branch and expressed S100β, a Schwann cell marker. Scale bar = 20 μm. (c) The GFP expressing MSC-like cells (yellow arrow and inset) engrafted in a sural nerve. Some engrafted cells surrounded a nerve fiber (inset). Some engrafted cells resided close to a perineurium (yellow arrow head). Scale bar = 50 μm. IB4: isolectin GS-IB4.
