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BioMed Research International
Volume 2013 (2013), Article ID 263594, 10 pages
http://dx.doi.org/10.1155/2013/263594
Research Article

Efficiency of Barley Bran and Oat Bran in Ameliorating Blood Lipid Profile and the Adverse Histological Changes in Hypercholesterolemic Male Rats

1Biochemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia
2Bioinformatics Department, Genetic Engineering and Biotechnology Research Institute, Minufiya University, P.O. Box 79, Sadat City, Egypt
3Badreddin Clinic, Jeddah, Saudi Arabia

Received 19 March 2013; Revised 1 June 2013; Accepted 11 July 2013

Academic Editor: Anne Pihlanto

Copyright © 2013 Haddad A. El Rabey et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. M. Sacks, M. A. Pfeffer, L. A. Moye et al., “The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels,” The New England Journal of Medicine, vol. 335, no. 14, pp. 1001–1009, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. P. S. Nijjar, F. M. Burke, A. Bloesch, and D. J. Rader, “Role of dietary supplements in lowering low-density lipoprotein cholesterol: a review,” Journal of Clinical Lipidology, vol. 4, no. 4, pp. 248–258, 2010. View at Scopus
  3. K. M. Behall, D. J. Scholfield, and J. Hallfrisch, “Lipids significantly reduced by diets containing barley in moderately hypercholesterolemic men,” Journal of the American College of Nutrition, vol. 23, no. 1, pp. 55–62, 2004. View at Scopus
  4. M. H. Alu'datt, T. Rababah, K. Ereifej et al., “Effects of barley flour and barley protein isolate on chemical, functional, nutritional and biological properties of Pita bread,” Food Hydrocolloids, vol. 26, no. 1, pp. 135–143, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. P. Sullivana, E. Arendt, and E. Gallaghera, “The increasing use of barley and barley by-products in the production of healthier baked goods,” Trends in Food Science & Technology, vol. 29, pp. 124–134, 2013.
  6. S. R. Glore, D. Van Treeck, A. W. Knehans, and M. Guild, “Soluble fiber and serum lipids: a literature review,” Journal of the American Dietetic Association, vol. 94, no. 4, pp. 425–436, 1994. View at Publisher · View at Google Scholar · View at Scopus
  7. A. S. Truswell, “Dietary fibre and plasma lipids,” European Journal of Clinical Nutrition, vol. 49, no. 3, pp. S105–S109, 1995. View at Scopus
  8. Y. Malkki, K. Pelkonen, O. Myllymaki, R. Torronen, O. Hanninen, and K. Syrjanen, “Effects of oat bran concentrate on rat serum lipids and liver fat infiltration,” European Journal of Clinical Nutrition, vol. 49, no. 3, pp. S321–S324, 1995. View at Scopus
  9. E. Naumann, A. B. Van Rees, G. Önning, R. Öste, M. Wydra, and R. P. Mensink, “β-Glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations,” American Journal of Clinical Nutrition, vol. 83, no. 3, pp. 601–605, 2006. View at Scopus
  10. D. A. J. M. Kerckhoffs, G. Hornstra, and R. P. Mensink, “Cholesterol-lowering effect of β-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when β-glucan is incorporated into bread and cookies,” American Journal of Clinical Nutrition, vol. 78, no. 2, pp. 221–227, 2003. View at Scopus
  11. N. H. Aly, “Effect of dietary oat and wheat bran on biochemical changes in rats fed high fat-high cholesterol diets,” Journal of Applied Sciences Research, vol. 8, pp. 598–604, 2012.
  12. J. Chen, J. He, R. P. Wildman, K. Reynolds, R. H. Streiffer, and P. K. Whelton, “A randomized controlled trial of dietary fiber intake on serum lipids,” European Journal of Clinical Nutrition, vol. 60, no. 1, pp. 62–68, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. D. G. Stevenson, G. E. Inglett, D. Chen, A. Biswas, F. J. Eller, and R. L. Evangelista, “Phenolic content and antioxidant capacity of supercritical carbon dioxide-treated and air-classified oat bran concentrate microwave-irradiated in water or ethanol at varying temperatures,” Food Chemistry, vol. 108, no. 1, pp. 23–30, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. K. E. Charlton, L. C. Tapsell, M. J. Batterham et al., “Effect of 6 weeks' consumption of β-glucan-rich oat products on cholesterol levels in mildly hypercholesterolaemic overweight adults,” British Journal of Nutrition, vol. 1, pp. 1–11, 2011.
  15. R. A. Othman, M. H. Moghadasian, and P. J. H. Jones, “Cholesterol-lowering effects of oat β-glucan,” Nutrition Reviews, vol. 69, no. 6, pp. 299–309, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. J. M. Keenan, M. Goulson, T. Shamliyan, N. Knutson, L. Kolberg, and L. Curry, “The effects of concentrated barley β-glucan on blood lipids in a population of hypercholesterolaemic men and women,” British Journal of Nutrition, vol. 97, no. 6, pp. 1162–1168, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. J. J. Pins and H. Kaur, “A review of the effects of barley β-glucan on cardiovascular and diabetic risk,” Cereal Foods World, vol. 51, no. 1, pp. 8–11, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Åman, “Cholesterol-lowering effects of barley dietary fibre in humans: scientific support for a generic health claim,” Scandinavian Journal of Food and Nutrition, vol. 50, no. 4, pp. 173–176, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Araki, K. Ito, S. Aoe, and S. Ikegami, “Physiological functions of barley and the health claims on food labels,” Japanese Journal of Nutrition and Dietetics, vol. 67, pp. 235–251, 2009.
  20. American Institute of Nutrition, “Second report of AIN Ad Hoc Committee on standards for nutritional studies,” Journal of Nutrition, vol. 110, article 1726, 1980.
  21. Z. Moussavi, M. O. Plancke, O. P. Olivier Ph., D. Lesieur, J. C. Fruchart, and J. Sauzieres, “Lipid lowering actions of 7-(2-methylene butyryl)-(2H)-1,4-benzoxazin-3-(4H)-one derivatives in mice, rats and Syrian hamsters,” Clinica Chimica Acta, vol. 180, no. 1, pp. 35–44, 1989. View at Scopus
  22. F. L. Shinnick, M. J. Longacre, S. L. Ink, and J. A. Marlett, “Oat fiber: composition versus physiological function in rats,” Journal of Nutrition, vol. 118, no. 2, pp. 144–151, 1988. View at Scopus
  23. R. C. Jain, H. Khubnani, and A. Khubnani, “Action of garlic on the hyperlipidemia of experimental induced immune complex disease in rabbits,” Indian Journal of Pharmacology, vol. 29, no. 4, pp. 255–257, 1997. View at Scopus
  24. O. M. Ahmed, “Histopathological and biochemical evaluation of Liver and kidney lesions in streptozotocin diabetic rats treated with glimepiride and various plant extracts,” Journal of Union of Arab Biologists Cairo, vol. 164, pp. 585–625, 2001.
  25. H. B. Waynforth, Experimental Animal and Surgical Technique in the Rat, Academic Press, New York, NY, USA, 1980.
  26. W. Habig, M. Pabst, and W. J. Jakoby, “Intestinal glutathione S-transferase activity in flounder Platichthys flesus collected from contaminated and reference sites,” The Journal of Biological Chemistry, vol. 249, pp. 7130–77139, 1974.
  27. H. Aebi, “Catalase in vitro,” Methods in Enzymology, vol. 105, no. C, pp. 121–126, 1984. View at Publisher · View at Google Scholar · View at Scopus
  28. H. Ohkawa, N. Ohishi, and K. Yagi, “Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction,” Analytical Biochemistry, vol. 95, no. 2, pp. 351–358, 1979. View at Scopus
  29. R. A. Drury, E. A. Wallington, and R. Cancerson, Carlton's histopathological techniques, Oxford University Press, Oxford, UK, 4th edition, 1976.
  30. R. K. Newman, C. W. Newman, and H. Graham, “The hypocholesterolemic function of barley β-glucans,” Cereal Foods World, vol. 34, article 883, 1989.
  31. J. Czerwiński, E. Bartnikowska, H. Leontowicz et al., “Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in rats fed cholesterol-containing diets,” Journal of Nutritional Biochemistry, vol. 15, no. 10, pp. 622–629, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. K. M. Queenan, M. L. Stewart, K. N. Smith, W. Thomas, R. G. Fulcher, and J. L. Slavin, “Concentrated oat β-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial,” Nutrition Journal, vol. 6, article 6, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. Y. Malkki, S. S. Cho, and M. L. Dreher, “Oat fiber: production, composition, physicochemical properties, physiological effects, safety, and food applications,” in Handbook of Dietary Fiber, pp. 497–517, 2001.
  34. G. F. Keogh, G. J. S. Cooper, T. B. Mulvey et al., “Randomized controlled crossover study of the effect of a highly β-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men,” American Journal of Clinical Nutrition, vol. 78, no. 4, pp. 711–718, 2003. View at Scopus
  35. J. W. Anderson, “Dietary fiber and diabetes,” in Medical Aspects of Dietary Fiber, G. A. Spiller and R. M. Kay, Eds., pp. 193–221, Plenum Medical, New York, NY, USA, 1980.
  36. J. T. Braaten, P. J. Wood, F. W. Scott et al., “Oat β-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects,” European Journal of Clinical Nutrition, vol. 48, no. 7, pp. 465–474, 1994. View at Scopus
  37. T. Kishida, H. Nogami, H. Ogawa, and K. Ebihara, “The hypocholesterolemic effect of high amylose cornstarch in rats is mediated by an enlarged bile acid pool and increased fecal bile acid excretion, not by cecal fermented products,” Journal of Nutrition, vol. 132, no. 9, pp. 2519–2524, 2002. View at Scopus
  38. M. M. Mahfouz and F. A. Kummerow, “Cholesterol-rich diets have different effects on lipid peroxidation, cholesterol oxides, and antioxidant enzymes in rats and rabbits,” Journal of Nutritional Biochemistry, vol. 11, no. 5, pp. 293–302, 2000. View at Publisher · View at Google Scholar · View at Scopus
  39. J. Balkan, S. Doǧru-Abbasoǧlu, G. Aykaç-Toker, and M. Uysal, “The effect of a high cholesterol diet on lipids and oxidative stress in plasma, liver and aorta of rabbits and rats,” Nutrition Research, vol. 24, no. 3, pp. 229–234, 2004. View at Publisher · View at Google Scholar · View at Scopus
  40. E. S. Schaeffner, T. Kurth, G. C. Curhan et al., “Cholesterol and the risk of renal dysfunction in apparently healthy men,” Journal of the American Society of Nephrology, vol. 14, no. 8, pp. 2084–2091, 2003. View at Scopus
  41. R. Trevisan, A. R. Dodesini, and G. Lepore, “Lipids and renal disease,” Journal of the American Society of Nephrology, vol. 17, no. 2, pp. S145–S147, 2006. View at Publisher · View at Google Scholar · View at Scopus
  42. M. K. Abdel-Rahman, “Influence of dietary fat on renal function, lipid profile, sex hormones, and electrolyte balance in rats,” European Journal of Lipid Science and Technology, vol. 112, no. 10, pp. 1166–1172, 2010. View at Publisher · View at Google Scholar · View at Scopus
  43. D. S. Rampton, S. L. Cohen, and V. B. De Crammond, “Treatment of chronic renal failure with dietary fiber,” Clinical Nephrology, vol. 21, no. 3, pp. 159–163, 1984. View at Scopus
  44. M. E. Altunkaynak, E. Özbek, B. Z. Altunkaynak, I. Can, D. Unal, and B. Unal, “The effects of high-fat diet on the renal structure and morphometric parametric of kidneys in rats,” Journal of Anatomy, vol. 212, no. 6, pp. 845–852, 2008. View at Publisher · View at Google Scholar · View at Scopus
  45. J. Dimitrova-Shumkovska, L. Veenman, T. Ristoski, S. Leschiner, and M. Gavish, “Chronic high fat, high cholesterol supplementation decreases 18 kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta,” Food and Chemical Toxicology, vol. 48, no. 3, pp. 910–921, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. A. Ouvrier, G. Alves, C. Damon-Soubeyrand et al., “Dietary cholesterol-induced post-testicular infertility,” PLoS ONE, vol. 6, no. 11, Article ID e26966, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. H. Sekena, M. A. Abdel-Wahab, A. M. Mahmoud, and M. Azza, “Chemoprevention of Barley and Sage against acrylamide-Induced genotoxic, biochemical and histopathological alterations in rats,” Egyptian Journal of Hospital Medicine, vol. 15, pp. 40–56, 2004.