Research Article

The Steady-State Serum Concentration of Genistein Aglycone Is Affected by Formulation: A Bioequivalence Study of Bone Products

Table 1

Composition of three formulations for bone, a medical food indicated for osteopenia/osteoporosis, the Squadrito study formulation, and the OTC bone supplement. All minerals are given as elemental mass.

ConstituentMedical foodSquadrito study formulationOTC bone supplement

Dosage formCapsuleTabletTablet
Daily dose224
Genistein aglycone54 mg54 mg54 mg
Vitamin D3400 IU800 IU800 IU
Calcium (elemental)120 mg1000 mg1200 mg
Magnesium (elemental)100 mg
Zinc (elemental)8 mg15 mg
Copper (elemental)2 mg
Manganese (elemental)4 mg
Molybdenum (elemental)150  g
Boron (elemental)500  g

IU: international units.
OTC: over-the-counter.