Changes in the Mucus Barrier during Cisplatin-Induced Intestinal Mucositis in Rats

Figure 3

Time-course of the mucin content of the gastrointestinal mucosa. The animals were given cisplatin 6 mg/kg i.v. and were sacrificed at various time points (1, 3, 7, and 11 days) after treatment. Mucin content is expressed as micrograms of Fr-1 hexose per gram of dry tissue weight for each type of mucosa. Data are presented as means ± SE (𝑛=4-5). ^∗𝑃<0.05 and ^∗∗𝑃<0.01.

(a) Stomach

(b) Jejunum

(c) Ileum

(d) Colon