About this Journal Submit a Manuscript Table of Contents
BioMed Research International
Volume 2013 (2013), Article ID 276417, 6 pages
http://dx.doi.org/10.1155/2013/276417
Research Article

Influence of Heavy Metal Stress on Antioxidant Status and DNA Damage in Urtica dioica

1Faculty of Medical Sciences, Goce Delčev University, Krste Misirkov Street bb, P.O. Box 201, 2000 Štip, Macedonia
2Faculty of Pharmacy, Ss. Cyril and Methodius University, 1000 Skopje, Macedonia
3Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, 1000 Skopje, Macedonia

Received 2 April 2013; Accepted 20 May 2013

Academic Editor: Brad Upham

Copyright © 2013 Darinka Gjorgieva et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Cargnelutti, L. A. Tabaldi, R. M. Spanevello et al., “Mercury toxicity induces oxidative stress in growing cucumber seedlings,” Chemosphere, vol. 65, no. 6, pp. 999–1006, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. F. van Assche and H. Clijsters, “Effects of metals on enzyme activity in plants,” Plant, Cell & Environment, vol. 13, no. 3, pp. 195–206, 1990.
  3. V. Dixit, V. Pandey, and R. Shyam, “Differential antioxidative responses to cadmium in roots and leaves of pea (Pisum sativum L. cv. Azad),” Journal of Experimental Botany, vol. 52, no. 358, pp. 1101–1109, 2001. View at Scopus
  4. S. Verma and R. S. Dubey, “Lead toxicity induces lipid peroxidation and alters the activities of antioxidant enzymes in growing rice plants,” Plant Science, vol. 164, no. 4, pp. 645–655, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. I. F. F. Benzie and J. J. Strain, “The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay,” Analytical Biochemistry, vol. 239, no. 1, pp. 70–76, 1996. View at Publisher · View at Google Scholar · View at Scopus
  6. D. Savva, “Use of DNA fingerprinting to detect genotoxic effects,” Ecotoxicology and Environmental Safety, vol. 41, no. 1, pp. 103–106, 1998. View at Publisher · View at Google Scholar · View at Scopus
  7. F. A. Atienzar and A. N. Jha, “The random amplified polymorphic DNA (RAPD) assay and related techniques applied to genotoxicity and carcinogenesis studies: a critical review,” Mutation Research, vol. 613, no. 2-3, pp. 76–102, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. M. R. Enan, “Application of random amplified polymorphic DNA (RAPD) to detect the genotoxic effect of heavy metals,” Biotechnology and Applied Biochemistry, vol. 43, no. 3, pp. 147–154, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. G. Kekec, M. S. Sakcali, and I. Uzonur, “Assessment of genotoxic effects of boron on wheat (Triticum aestivum L.) and Bean (Phaseolus vulgaris L) by Using RAPD analysis,” Bulletin of Environmental Contamination and Toxicology, vol. 84, no. 6, pp. 759–764, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. D. Gjorgieva, T. Kadifkova-Panovska, S. Mitrev et al., “Assessment of the genotoxicity of heavy metals in Phaseolus vulgaris L as a model plant system by Random Amplified Polymorphic DNA (RAPD) analysis,” Journal of Environmental Science and Health A, vol. 47, no. 3, pp. 366–373, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Diatta, W. Grzebisz, and K. Apolinarska, “A study of soil pollution by heavy metals in the city of Poznan (Poland) using dandelion (Taraxacum officinale Web) as a bioindicator,” Electronic Journal of Polish Agricultural Universities, vol. 6, no. 2, 01, 2003.
  12. European Environmental Agency, Soil Pollution by Heavy Metals. Europe’s Environment, The Dobris Assessment, Office des publications, Luxembourg, 1995.
  13. I. Gülçin, O. I. Küfrevioğlu, M. Oktay, and M. E. Büyükokuroğlu, “Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.),” Journal of Ethnopharmacology, vol. 90, no. 2-3, pp. 205–215, 2004.
  14. A. Tahri, S. Yamani, A. Legssyer et al., “Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat,” Journal of Ethnopharmacology, vol. 73, no. 1-2, pp. 95–100, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. J. J. Lichius and C. Muth, “The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse,” Planta Medica, vol. 63, no. 4, pp. 307–310, 1997. View at Publisher · View at Google Scholar · View at Scopus
  16. National Environmental Action Plan (NEAP), Ministry of Urban planning, construction and environment, Skopje, Macedonia, 1996.
  17. L. Barandovski, M. Cekova, M. V. Frontasyeva et al., “Atmospheric deposition of trace element pollutants in Macedonia studied by the moss biomonitoring technique,” Environmental Monitoring and Assessment, vol. 138, no. 1–3, pp. 107–118, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Stafilov, R. Šajn, Z. Pančevski, B. Boev, M. V. Frontasyeva, and L. P. Strelkova, Geochemical Atlas of Veles and the Environs, Faculty of natural Sciences and mathematics-Skopje, Skopje, Macedonia, 2008.
  19. T. Stafilov, R. Šajn, Z. Pančevski, B. Boev, M. V. Frontasyeva, and L. P. Strelkova, “Heavy metal contamination of topsoils around a lead and zinc smelter in the Republic of Macedonia,” Journal of Hazardous Materials, vol. 175, no. 1–3, pp. 896–914, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Gjorgieva, T. Kadifkova-Panovska, K. Bačeva, and T. Stafilov, “Assessment of heavy metal pollution in Republic of Macedonia using a plant assay,” Archives of Environmental Contamination and Toxicology, vol. 60, no. 2, pp. 233–240, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. A. P. Murphy, M. Coudert, and J. Barker, “Plants as biomarkers for monitoring heavy metal contaminants on landfill sites using sequential extraction and inductively coupled plasma atomic emission spectrophotometry (ICP-AES),” Journal of Environmental Monitoring, vol. 2, no. 6, pp. 621–627, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Grubor, “Lead uptake, tolerance, and accumulation exhibited by the plants Urtica dioica and Sedum spectabile in contaminated soil without additives,” Archives of Biological Sciences, vol. 60, no. 2, pp. 239–244, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Kabata-Pendias and H. Pendias, Elements in Soils and Plants, CRC Press, Boca Raton, Fla, USA, 2nd edition, 1992.
  24. A. Kloke, D. C. Sauerbeck, and H. Vetter, “The contamination of plants and soils with heavy metals and the transport of metals in terrestrial food chains,” in Changing Metal Cycles and Human Health, J. O. Nriagu, Ed., pp. 113–141, Springer, Berlin, Germany, 1984.
  25. S. E. Allen, Chemical Analyses of Ecological Material, Blackwell Scientific Publications, Oxford, UK, 2nd edition, 1989.
  26. A. Maiga, D. Diallo, R. Bye, and B. S. Paulsen, “Determination of some toxic and essential metal ions in medicinal and edible plants from Mali,” Journal of Agricultural and Food Chemistry, vol. 53, no. 6, pp. 2316–2321, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. M. M. Özcan and M. Akbulut, “Estimation of minerals, nitrate and nitrite contents of medicinal and aromatic plants used as spices, condiments and herbal tea,” Food Chemistry, vol. 106, no. 2, pp. 852–858, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Meir, J. Kanner, B. Akiri, and S. Philosoph-Hadas, “Determination and involvement of aqueous reducing compounds in oxidative defense systems of various senescing leaves,” Journal of Agricultural and Food Chemistry, vol. 43, no. 7, pp. 1813–1819, 1995. View at Publisher · View at Google Scholar · View at Scopus
  29. Y. S. Velioglu, G. Mazza, L. Gao, and B. D. Oomah, “Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products,” Journal of Agricultural and Food Chemistry, vol. 46, no. 10, pp. 4113–4117, 1998. View at Scopus
  30. G. Noctor and C. H. Foyer, “Ascorbate and glutathione: keeping active oxygen under control,” Annual Review of Plant Biology, vol. 49, pp. 249–279, 1998. View at Scopus
  31. K. Asada, “The water-water cycle in chloroplasts: scavenging of active oxygens and dissipation of excess photons,” Annual Review of Plant Biology, vol. 50, pp. 601–639, 1999. View at Scopus
  32. A. Schützendübel and A. Polle, “Plant responses to abiotic stresses: heavy metal-induced oxidative stress and protection by mycorrhization,” Journal of Experimental Botany, vol. 53, no. 372, pp. 1351–1365, 2002. View at Scopus
  33. O. Shainberg, B. Rubin, H. D. Rabinowitch, Y. Libal, and E. Tel-Or, “Acclimation of beans to oxidative stress by treatment with sublethal iron levels,” Journal of Plant Physiology, vol. 157, no. 1, pp. 93–99, 2000. View at Scopus
  34. T. Ishikawa, Z.-S. Li, Y.-P. Lu, and P. A. Rea, “The GS-X pump in plant, yeast, and animal cells: structure, function, and gene expression,” Bioscience Reports, vol. 17, no. 2, pp. 189–207, 1997. View at Publisher · View at Google Scholar · View at Scopus
  35. T. Gichner, “DNA damage induced by indirect and direct acting mutagens in catalase-deficient transgenic tobacco: cellular and acellular comet assays,” Mutation Research, vol. 535, no. 2, pp. 187–193, 2003. View at Publisher · View at Google Scholar · View at Scopus
  36. S. Cenkci, M. Yildiz, I. H. Ciǧerci, M. Konuk, and A. Bozdaǧ, “Toxic chemicals-induced genotoxicity detected by random amplified polymorphic DNA (RAPD) in bean (Phaseolus vulgaris L.) seedlings,” Chemosphere, vol. 76, no. 7, pp. 900–906, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. C. C. Hon, Y. C. Chow, F. Y. Zeng, and F. C. C. Leung, “Genetic authentication of ginseng and other traditional Chinese medicine,” Acta Pharmacologica Sinica, vol. 24, no. 9, pp. 841–846, 2003. View at Scopus
  38. H. de Wolf, R. Blust, and T. Backeljau, “The use of RAPD in ecotoxicology,” Mutation Research, vol. 566, no. 3, pp. 249–262, 2004. View at Publisher · View at Google Scholar · View at Scopus