MMP1, MMP9, and COX2 Expressions in Promonocytes Are Induced by Breast Cancer Cells and Correlate with Collagen Degradation, Transformation-Like Morphological Changes in MCF-10A Acini, and Tumor Aggressiveness

<table>Colocalization of MDA-MB-231 and U937 cells with areas of ECM degradation. Confocal microscopy representative microphotographs of MDA-MB-231 and U937 cocultures. Collagen degradation (upper left panel), optical image of an MDA-MB-231 cell conglomerate (upper right panel), U937 cells labeled with CellTracker Orange (lower left panel), and the merge of all images (lower right panel). The epithelial morphology of MDA-MB-231 cells is pointed with a white arrow. Optical magnification 200x.</table>

BioMed Research International

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Figure 3

Figure 3: MMP1, MMP9, and COX2 Expressions in Promonocytes Are Induced by Breast Cancer Cells and Correlate with Collagen Degradation, Transformation-Like Morphological Changes in MCF-10A Acini, and Tumor Aggressiveness 

Figure 3 | MMP1, MMP9, and COX2 Expressions in Promonocytes Are Induced by Breast Cancer Cells and Correlate with Collagen Degradation, Transformation-Like Morphological Changes in MCF-10A Acini, and Tumor Aggressiveness 