Tamoxifen Treatment in Hamsters Induces Protection during Taeniosis by Taenia solium
Figure 3
Tamoxifen impairs the in vivo establishment of Taenia solium. Hamsters were subcutaneously treated with 1 mg/Kg body weight tamoxifen and orally infected using four viable T. solium cysticerci each. Control = Nonmanipulated animals, infected with four viable cysticerci each; Vehicle = animals subcutaneously treated with 0.06% ethanol-saline solution, infected with four viable cysticerci each. (a) Evaluation of the number of duodenum-anchored tapeworms at day fifteen post-infection. (b) Assessment of the length of recovered tapeworms at day fifteen post-infection. Data were pooled from two independent experiments using ten animals per group in each experimental series and cysticerci obtained from two different pigs. Results are presented as mean ± standard deviation. Differences were considered significant when . **Significant differences concerning control groups.
