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BioMed Research International
Volume 2013 (2013), Article ID 281230, 11 pages
http://dx.doi.org/10.1155/2013/281230
Review Article

The Role of Magnetic Nanoparticles in the Localization and Treatment of Breast Cancer

Department of Research Oncology, King’s College London, Guy’s Hospital Campus, Great Maze Pond, London SE1 9RT, UK

Received 1 January 2013; Accepted 17 June 2013

Academic Editor: B. E. Kumara Swamy

Copyright © 2013 M. Ahmed and M. Douek. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The role of magnetic nanoparticles (MNPs) in medical applications is rapidly developing. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The current use of MNPs in breast cancer falls into four main groups: (1) imaging of primary and metastatic disease, (2) sentinel lymph node biopsy (SLNB), (3) drug delivery systems, and (4) magnetic hyperthermia. The current evidence for the use of MNPs in these fields is mounting, and potential cutting-edge clinical applications, particularly with relevance to the fields of breast oncological surgery, are emerging.