Different Levels in Orexin Concentrations and Risk Factors Associated with Higher Orexin Levels: Comparison between Detoxified Opiate and Methamphetamine Addicts in 5 Chinese Cities
Table 2
Unadjusted odds ratios and 95% confidence interval for the relationship between a concentration above the median of the orexin (pg/mL) and demographic characteristics and history of drug use among different groups.
Variables
Opiate group
MA* group
N
Median (IQR†)
P
OR (95% CI)
N
Median (IQR†)
P
OR (95% CI)
Age (year)
≤35
119
58.13 (40.89–87.78)
0.787
0.937 (0.585–1.501)
78
42.42 (28.06–77.70)
0.153
1
35
166
60.24 (39.98–103.14)
1
28
31.90 (23.04–58.78)
1.899 (0.788–4.577)
Regular median dosage (g/each time)
0.5
196
56.92 (39.20–93.73)
0.303
1
63
40.47 (25.14–92.00)
0.342
1
0.5
89
62.08 (41.55–95.38)
0.768 (0.464–1.270)
49
36.33 (25.96–50.81)
1.439 (0.680–3.046)
Routes of administration at addiction phase
Chasing the dragon
181
55.61 (39.60–88.87)
0.033
1
58
43.09 (29.56–77.70)
0.450
1
Injection
79
74.29 (45.80–136.40)
1.609 (0.676–3.831)
—
—
—
Others
25
52.07 (36.34–74.86)
2.904 (1.140–7.393)
54
36.33 (24.50–62.00)
0.751 (0.357–1.579)
Months of drug use
≤12
210
59.87 (40.73–94.51)
0.610
1
36
43.31 (24.66–90.76)
0.419
1
12
75
57.72 (40.04–92.73)
0.872 (0.514–1.478)
76
37.14 (26.44–62.37)
1.389 (0.626–3.081)
Exposure was defined as the above median concentration of orexin. IQR; interquartile range. Methamphetamine.
