Characterization of an Antihypertensive Angiotensin I-Converting Enzyme Inhibitory Peptide from the Edible Mushroom Hypsizygus marmoreus

Table 1

Comparison of sequence and ACE inhibitory activity between ACE inhibitory peptides from some mushrooms and Hypsizygus  marmoreus in this study.

Mushrooms	Peptide	Molecular; weight (Da)	IC50(mg/mL)^a	References
Pleurotus cornucopiae	RLPSEFDLSAFLRA	1622.85	0.460	Jang et al. 2011 [11]
	RLSGQTIEVTSEYLFRH	2037.26	1.140
Pholiota adiposa	GOGGP	414.00	0.044	Koo et al. 2006 [10]
Tricholoma giganteum	GOP	301.10	0.040	Lee et al. 2004 [9]
Hypsizygus marmoreus	LSMGSASLSP	567.30	0.190	This study
Captopril			17.9 nM	commercial drug

aThe concentration of an ACE inhibitor required to inhibit 50% of ACE activity.