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BioMed Research International
Volume 2013 (2013), Article ID 284821, 7 pages
Clinical Study

Epiretinal Membranes in Patients with Uveitis: Morphological and Functional Analysis with Spectral Domain Optical Coherence Tomography

1Department of Ophthalmology, Sapienza University of Rome, 15500161 Rome, Italy
2Servizio di Immunovirologia Oculare, Sapienza Università di Roma, Viale del Policlinico, 15500161 Rome, Italy

Received 9 April 2013; Revised 22 September 2013; Accepted 22 September 2013

Academic Editor: Timothy Y. Lai

Copyright © 2013 Ludovico Iannetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To correlate the uveitic epiretinal membrane (ERM) features using spectral-domain optical coherence tomography (SD-OCT) with visual acuity (VA). Methods. Forty-one eyes of 32 patients were included in this retrospective study. SD-OCT was performed in all patients and data were collected at the time of ERM diagnosis and at the final visit. Both best corrected visual acuity (BCVA) and ERM thickness were correlated with the morphological and clinical features. Results. Final BCVA was positively correlated with male sex and the focal pattern of ERM attachment and negatively correlated with IS/OS photoreceptor junction disruption . BVCA change showed a positive correlation with the age of ERM onset but a negative correlation with IS/OS photoreceptor disruption at the ERM diagnosis and the increase of central subfield thickness (CST) . Final ERM thickness correlated with the duration of uveitis and the duration of ERM . During the follow-up, ERM thickening correlated with male sex , posterior uveitis , uveitis duration , and broad attachment pattern . Conclusions. In the uveitic ERM, VA negatively correlates with IS/OS photoreceptor junction disruption and the increase of CST. ERM thickness is influenced by longer duration of both uveitis and ERM.