Research Article

Information Content-Based Gene Ontology Semantic Similarity Approaches: Toward a Unified Framework Theory

Table 1

Comparison of different IC-based approach parameters. In the GO term semantic similarity approaches, is the MICA between GO terms and , and is the number disjunctive common ancestors between terms and , the th being the MICA between and .

Family Approach Parameters

Annotation Lin
Relevance
Li et al.
GraSM

Wang et al. 1 1
Topology Zhang et al. 1
GO-Universal or 1