Research Article
Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae
Table 2
CAN1 mutation spectrum of wild-type yeast exposed to Mn2+.
| Base substitution mutations | Transitions (8/20) | Transversions (6/20) |
| G522A G550A C623T G670A G1196A(×2) G1555A (×2) | A312T A375C T380G A1417T (×2) A1645T |
| Frameshift mutations | Insertions (2/20) | Deletions (4/20) |
| T740 T628 | C417 T1143 G1259 G1474 |
|
|