Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae

Table 2

CAN1 mutation spectrum of wild-type yeast exposed to Mn²⁺.

Base substitution mutations
Transitions (8/20)	Transversions (6/20)
G522A; G550A; C623T; G670A; G1196A(×2); G1555A (×2)	A312T; A375C; T380G; A1417T (×2); A1645T
Frameshift mutations
Insertions (2/20)	Deletions (4/20)
T740; T628	C417; T1143; G1259; G1474