In Vitro Characterization of a Multifunctional Staphylokinase Variant with Reduced Reocclusion, Produced from Salt Inducible E. coli GJ1158
Figure 7
The effect of SRH and SAK on inhibition of ADP-induced platelet aggregation. (a) The amplitude-impedance aggregation results are displayed as ohms (Ω) at six minute. The SAK had negligible effect on inhibition platelet aggregation compared to SRH and did not increase with dose. Data represents a means ± SD of 3 independent experiments, which were performed in duplicate. (b) Whole blood aggregometer was used for antiplatelet aggregation study of SRH or SAK in whole blood. Data represent a means ± SD of 3 independent experiments, which were performed in duplicate. Results are expressed as a percentage inhibition in relation to platelets incubated with no recombinant proteins taken as 100%. There are significant statistical difference between the inhibitory effect of SRH and SAK for each concentration ().
