In Vitro and In Vivo Investigation of the Potential of Amorphous Microporous Silica as a Protein Delivery Vehicle

Table 1

Specific surface area of AMS determined from N₂ physisorption isotherms.

	Micropore volume^a (mm^3/g)	External surface area^a (m^2/g)	BET surface area (m^2/g)
AMS	260	15	518
BSA loaded	240	15	448
10 min release^b	230	13	440
6 h release^b	230	12	441
24 h release^b	220	13	404

aDetermined using the 𝑡-plot method; ^bafter elimination of the adsorbed BSA by calcination.