Anticestodal Activity of Endophytic Pestalotiopsis sp. on Protoscoleces of Hydatid Cyst Echinococcus granulosus

Table 1

Preliminary screening results of the selected endophytic strains against hydatid cyst Echinococcus granulosus. Endophytic Pestalotiopsis sp. extract shows promising activity.

Endophytic microbes; (crude extract 20 mg/mL)	Protoscolicidal activity (mortality^a) after incubation up to 30 min
	10 min			20 min			30 min
	Control	Dead	𝑀^∗∗	Control	Dead	𝑀^∗∗	Control	Dead	𝑀^∗∗
Nigrospora sp.	623±25.1	348±40.1	58	825±60.1	500±86.0	62	706±82.7	479±52.9	70
Pestalotiopsis sp.	366±39.0	299±18.8	85	357±16.8	323±15.5	94	621±20.0	581±15.0	97
Colletotrichum sp.	372±7.37	216±14.5	59	674±15.0	425±28.3	66	677±24.4	469±25.8	70
Fusarium sp.	762±17.5	455±19.5	61	913±17.7	586±25.6	66	541±27.7	355±14.5	69
Chaetomium sp.	663±54.9	382±76.6	59	917±17.7	550±46.7	63	552±26.7	332±28.3	64
Praziquantel	391±43.1	376±22.5	97	354±39.5	348±16.2	99	592±44.2	584±18.1	100
PBS*	591±28.5	8±2.60	~1	812±65.3	29±11.0	~2	517±13.8	15±16.1	~4

∗PBS: phosphate buffer saline; ^∗∗𝑀: percentage mortality; ^aas determined by adopting eosin red exclusion method (see material and methods for detail).