Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus

Table 2

Genotype and allele frequencies of IL-6 −174G/C polymorphism in dermatomyositis and systemic lupus erythematosus patients and controls.

Genotype	DM	SLE	Controls
𝑁 = number of patients	𝑁=35	𝑁=52	𝑁=80
−174G/C
GG	14 (40.0%)	29 (55.8%)	32 (40.0%)
GC	11 (31.4%)	13 (25.0%)	21 (26.3%)
CC	10 (28.6%)	10 (19.2%)	27 (33.7%)
G	55.7%	68.3%	53.1%
C	44.3%	34.6%	46.9%
𝑃 value	NS*	G—P = 0.01

∗Not significant.