Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus

Table 3

Allele and genotype frequency of the IL-6 −174G/C polymorphism in females with dermatomyositis and systemic lupus erythematosus and in controls.

Genotype	DM	SLE	Controls
𝑁 = number of females	𝑁=22	𝑁=43	𝑁=58
−174G/C
GG	8 (36.4%)	26 (60.5%)	20 (34.5%)
GC	6 (27.2%)	10 (23.2%)	14 (24.1%)
CC	8 (36.4%)	7 (16.3%)	24 (41.4%)
G	50.0%	72.1%	46.6%
C	50.0%	27.9%	53.4%
𝑃 value	NS*	GG—0.008; G—0.0002

∗Not significant.