Research Article
Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus
Table 4
Comparison between the genotypes and ACR criteria.
| | Genotype | GG () | GC () | CC () | value |
| | Malar rash | 20 (69.0%) | 5 (38.5%) | 9 (90.0%) | NS* | | Discoid rash | 6 (20.7%) | 3 (23.1%) | 0 (0.0%) | NS | | Photosensitivity | 17 (58.6%) | 8 (61.5%) | 5 (50.0%) | NS | | Oral ulcer | 1 (3.4%) | 2 (15.4%) | 0 (0.0%) | NS | | Arthritis | 18 (56.5%) | 9 (69.2%) | 7 (70.0%) | NS | | Serositis | 6 (20.7%) | 4 (30.8%) | 1 (10.0%) | NS | | Renal disease | 29 (100.0%) | 13 (100.0%) | 10 (100.0%) | — | | Neurological disease | 6 (26.1%) | 2 (15.4%) | 2 (20.0%) | NS | | Haematological disease | 11 (37.9%) | 4 (30.8%) | 5 (50.0%) | NS | | Immunological disease (anti-dsDNA, anti-Sm, and antiphospholipid Ab) | 20 (69.0%)
| 6 (46.2%)
| 6 (60.0%)
| NS
| | ANA | 22 (75.9%) | 7 (53.8%) | 7 (70.0%) | NS |
|
|
Not significant.
|
