Factors Affecting Bilirubin Levels during First 48 Hours of Life in Healthy Infants
Table 2
Relationship of delivery modes and anesthesia types with first feeding, first meconium passage times, feeding types, and bilirubin levels.
C/S
Vaginal (n: 104)
C/S (n: 284)
General anesthesia thiopental (n: 39)
Epidural levobupivacaine (n: 23)
Spinal hyperbaric bupivacaine (n: 222)
First feeding (hour)†
0.50 (0.5) 0.1–3
1.50 (1) 0.2–3.0
0.00
2.00 (1) 0.4–3.0
2.00 (1) 0.5–3.0
1.00 (1) 0.2–3.0
0.20
Breastfeeding‡
77.9 (n: 81)
50.3 (n: 142)
41.0 (n: 16)
56.5 (n: 13)
52.7 (n: 117)
Mixed feeding‡
22.1 (n: 23)
49.2 (n: 139)
0.00
56.4 (n: 22)
43.5 (n: 10)
46.8 (n: 104)
0.29
Formula‡
0 (n: 0)
0.5 (n: 1)
2.6 (n: 1)
0 (n: 0)
0.5 (n: 1)
Meconium passage (hour)†
6.00 (7) 0–26
6.00 (9) 0–36
0.50
12.00 (8) 0–36
5.00 (6) 1–24
6.00 (7) 0–28
Cord bilirubin† (mg/dL)
1.60 (0.7) 0.3–4.5
1.60 (0.6) 0.5–4
0.62
1.70 (0.9) 1–3.5
1.50 (0.8) 0.9–2.9
1.60 (0.6) 0.5–4.0
0.70
24 hours bilirubin† (mg/dL)
4.20 (2.1) 0.9–9
4.20 (2.1) 0.1–10.6
0.86
3.70 (2.2) 1.5–8
4.30 (2.2) 1.8–7.9
4.20 (2.1) 0.1–10.6
0.52
48 hours bilirubin† (mg/dL) (median)
6.50 (2.9) 1.8–14.9
6.60 (2.5) 0.6–13.9
0.45
6.50 (2.7) 2.6–12
6.60 (2.7) 3.4–12
6.65 (2.4) 0.6–13.9
0.86
Data presented as median (interquartile range: IQR) (min–max). Data presented as number (%). The statistical difference is due to general anesthesia (thiopental) (Kruskal-Wallis test).