Gsk-3<i>β</i> Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats

<table>Infarct size (IS), expressed as a percentage of risk area, in nonischemic control (NIC), ischemic control (IC), preconditioned (PRE), postconditioned (POS), <svg height="11.3625" id="M84" style="vertical-align:-0.15013pt" version="1.1" viewbox="0 0 63.862499 11.3625" width="63.862499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> (wortmannin), <svg height="11.6875" id="M85" style="vertical-align:-0.20473pt" version="1.1" viewbox="0 0 64.487503 11.6875" width="64.487503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, lithium, and IMI treated hearts. Observe that all interventions decreased the infarct size detected in IC hearts. W abolished the protection achieved by PRE and POS. *<svg height="11.375" id="M86" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus IC; <sup>#</sup><svg height="11.375" id="M87" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus PRE and POS.</table>

BioMed Research International

fig2

Figure 2

Figure 2: Gsk-3<i>β</i> Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats 

BioMed Research International

Gsk-3β Inhibitors Mimic the Cardioprotection Mediated by Ischemic Pre- and Postconditioning in Hypertensive Rats

Figure 2