Common Variant of FTO Gene, rs9939609, and Obesity in Pakistani Females

Table 3

Genotype and allele distribution of the rs9939609 variant of FTO gene in obese and non-obese subjects.

Genotype	All subjects		𝜒^2 /P/OR	Females		𝜒^2/P/OR	Males		𝜒^2/P/OR	>18 years		𝜒^2/P/OR	Females > 18 years		𝜒^2/P/OR	Males > 18 years		𝜒^2/P/OR	≤18 years		𝜒^2/P/OR
	Obese; 𝑛=239	Nonobese; 𝑛=130		Obese; 𝑛=128	Nonobese; 𝑛=71		Obese; 𝑛=111	Nonobese; 𝑛=59		Obese; 𝑛=161	Nonobese; 𝑛=85		Obese; 𝑛=97	Nonobese; 𝑛=41		Obese; 𝑛=64	Nonobese; 𝑛=44		Obese; 𝑛=78	Nonobese; 𝑛=45
	Codominant model
AA	6 (2%)	2 (1%)		4 (3%)	1 (1%)		2 (1.8%)	1 (1.6%)		4 (2%)	1 (1%)		3 (3%)	1 (2%)		1 (1.5%)	0		2 (2.6%)	0
TA	87 (36%)	34 (26%)	4.6/0.09	52 (41%)	16 (23%)	7.7/0.02	35 (31.5%)	18 (30.5%)	0.02/0.9	61 (38%)	20 (24%)	1.7/0.4	44 (45%)	7 (18%)	10.2/0.005	17 (26.5%)	13 (29.5%)	0.7/0.6	26 (33.3%)	15 (33.3%)	1.1/0.5
TT	146 (61%)	94 (72%)		72 (56%)	54 (76%)		74 (66.6%)	40 (67.7%)		96 (60%)	64 (75%)		50 (51%)	33 (80%)		46 (71.8%)	31 (70%)		50 (64%)	30 (66.6%)
	Dominant model
A/A + A/T	93 (39%)	36 (27%)		56 (44%)	17 (24%)		37 (33%)	19 (32.2%)		65 (40%)	21 (25%)		47 (48%)	8 (20%)		18 (28%)	13 (29.5%)		28 (36%)	15 (33.3%)
T/T	146 (61%)	94 (72%)	4.6/0.03/1.6	72 (56%)	54 (76%)	7.7/0.005/2.4	74 (66.6%)	40 (67.7%)	0.02/0.8/1.0	96 (60%)	64 (75%)	6/0.01/2	50 (51%)	33 (80%)	10.0/0.001/3.8	46 (72%)	31 (70%)	0.02/0.8/0.9	50 (64%)	30 (66.6%)	0.08/0.7/1.1
	Recessive model
A/A	6 (2%)	2 (1%)		4 (3%)	1 (2%)		2 (1.8%)	1 (1.6%)		4 (2%)	1 (1%)		3 (3%)	1 (2%)		1 (1.5%)	0		2 (2.6%)	0
A/T + T/T	233 (97%)	128 (98%)	0.3/0.5/1.6	124 (97%)	70 (98%)	0.5/0.4/2.2	109 (98%)	58 (98%)	0/1/1.0	157 (98%)	84 (99%)	0.3/0.5/2.1	94 (97%)	40 (98%)	0.04/0.8/1.2	63 (98.4%)	44 (100%)	0.6/0.4	76 (97.4%)	45 (100%)	0/0.5
	Alleles
A	99 (21%)	38 (15%)		60 (31%)	[18 (13%)]		39 (17.5%)	20 (16.9%)		69 (21%)	22 (13%)		50 (26%)	9 (11%)		19 (14.8%)	13 (14.8)		30 (19.3%)	15 (16.6%)
T	379 (79%)	222 (85%)	4.1/0.04/1.5	131 (69%)	124 (87%)	15.9/<0.0001/3.1	183 (82.5%)	98 (83%)	0.02/0.8/1.0	253 (79%)	148 (87%)	5.3/0.02/1.8	144 (74%)	73 (89%)	7.5/0.006/2.8	109 (85%)	75 (85.2%)	0/1/0.005	126 (80.7%)	75 (83.3%)	0.2/0.6/1.1

T = Wild; A = polymorphic.