Research Article
Stage-Stratified Analysis of Prognostic Significance of Bax-Interacting Factor-1 Expression in Resected Colorectal Cancer
Table 2
Relationships between clinicopathological factors and Bif-1 expression patterns.
| | | Bif-1 | | | | Low, (%) | High, (%) |
| | T stage | | | 0.839 | | 1 | 1 (0.8) | 1 (0.8) | | | 2 | 28 (21.4) | 21 (17.5) | | | 3 | 80 (61.0) | 74 (61.7) | | | 4 | 22 (16.8) | 24 (20.0) | | | Lymph node involvement | | | 0.068 | | No | 63 (48.1) | 44 (36.7) | | | Yes | 68 (51.9) | 76 (63.3) | | | Distant metastasis | | | 0.019* | | No | 109 (83.2) | 85 (70.8) | | | Yes | 22 (16.8) | 35 (29.2) | | | Stage | | | 0.091 | | I | 22 (16.8) | 15 (12.5) | | | II | 36 (27.5) | 24 (20) | | | III | 51 (38.9) | 46 (38.3) | | | IV | 22 (16.8) | 35 (29.2) | 0.022*† | | Site of primary tumor | | | 0.034* | | Right colon | 23 (17.6) | 38 (31.7) | | | Left colon | 48 (36.6) | 36 (30.0) | | | Rectum | 60 (45.8) | 46 (38.3) | | | Histology | | | 0.631 | | Tubular adenocarcinoma | 117 (89.3) | 108 (90) | | | Others‡ | 14 (10.7) | 12 (10) | | | Lymphovascular invasion | | | 0.434 | | Negative | 51 (38.9) | 41 (34.2) | | | Positive | 80 (61.1) | 79 (65.8) | |
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Statistically significant ().
†When pathologic stage was divided into stages I–III and IV.
‡Mucinous carcinoma (); signet-ring-cell carcinoma ().
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