Table 2: Relationships between clinicopathological factors and Bif-1 expression patterns.

Bif-1
Low, (%)High, (%)

T stage0.839
 11 (0.8)1 (0.8)
 228 (21.4)21 (17.5)
 380 (61.0)74 (61.7)
 422 (16.8)24 (20.0)
Lymph node involvement0.068
 No63 (48.1)44 (36.7)
 Yes68 (51.9) 76 (63.3)
Distant metastasis 0.019*
 No109 (83.2)85 (70.8)
 Yes22 (16.8)35 (29.2)
Stage0.091
 I22 (16.8)15 (12.5)
 II36 (27.5)24 (20)
 III51 (38.9)46 (38.3)
 IV22 (16.8)35 (29.2) 0.022*†
Site of primary tumor 0.034*
 Right colon23 (17.6)38 (31.7)
 Left colon48 (36.6)36 (30.0)
 Rectum60 (45.8)46 (38.3)
Histology0.631
 Tubular adenocarcinoma117 (89.3)108 (90)
 Others14 (10.7)12 (10)
Lymphovascular invasion0.434
 Negative51 (38.9)41 (34.2)
 Positive80 (61.1)79 (65.8)

Statistically significant ( ).
When pathologic stage was divided into stages I–III and IV.
Mucinous carcinoma ( ); signet-ring-cell carcinoma ( ).