Hp-𝜷-CD-Voriconazole In Situ Gelling System for Ocular Drug Delivery: In Vitro, Stability, and Antifungal Activities Assessment

Table 1

Physiochemical characterization of in situ gels of Voriconazole, mean ± SD; 𝑛 = 3.

Formulations	Concentration		Gelation temperature (°C)	Drug content; %	pH
	*PF-68	*Na alginate
VG1	14	0.5	37.33 ± 0.73	96.98 ± 1.34	6.8
VG2	14	1	36.50 ± 0.35	96.34 ± 2.00	6.9
VG3	14	1.5	35.70 ± 0.36	93.33 ± 1.26	7.0
VG4	15	0.5	33.80 ± 0.40	92.34 ± 2.15	6.9
VG5	15	1	32.60 ± 0.30	94.91 ± 0.372	7.1
VG6	15	1.5	30.83 ± 0.65	99.01 ± 2.79	7.4
VG7	16	0.5	29.63 ± 0.51	97.09 ± 1.90	6.9
VG8	16	1	28.36 ± 0.41	92.34 ± 0.66	6.8
VG9	16	1.5	24.36 ± 0.41	91.41 ± 0.51	7.2

∗PF 68—Pluronic 68 or Poloxamer 118.
∗Na alginate—sodium alginate.