Research Article

Hp- -CD-Voriconazole In Situ Gelling System for Ocular Drug Delivery: In Vitro, Stability, and Antifungal Activities Assessment

Table 5

A comparative study of anti-fungal activity of voriconazole in situ gel against Candida albicans and Aspergillus fumigatus.

S.NO.SolutionMean of diameter of zone of inhibition
(mm) ± SE
Range of zone size
(mm)
Coefficient of
variance
(%)

Candida albicans Test32.33 ± 0.1632.11–32.480.49
Control 110.04 ± 0.0310.01–10.120.30
Control 212.05 ± 0.0412.01–12.090.04
Aspergillus fumigates Test68.19 ± 0.5668.01–69.010.81
Control 110.02 ± 0.0110.01–10.140.15
Control 212.07 ± 0.0212.05–12.090.17

Test—VG9 formulation.
Control 1—VG9 formulation without drug.
Control 2—VG9 formulation without HP-β-CD.