Antioxidant and Toxicity Studies of 50% Methanolic Extract of Orthosiphon stamineus Benth

Table 2

(a) Haematological values of male rats treated with 50% methanolic extract of Orthosiphon stamineus for 28 days. (b) Haematological values of female rats treated with 50% methanolic extract of Orthosiphon stamineus for 28 days (cont’).

(a)

	Unit	Treatment for 28 days
		Control	50% methanolic extract of Orthosiphon stamineus
			1250 mg/kg	2500 mg/kg	5000 mg/kg
Male
White blood cell count	10^9/L	9.57±0.32	11.05±0.48	10.78±0.59	10.73±0.21
Neutrophils	10^9/L	2.46±0.18	3.09±0.22	3.15±0.31	3.18±0.43
Lymphocytes	10^9/L	6.67±0.24	6.94±0.46	6.72±0.29	6.67±0.41
Monocytes	10^9/L	0.24±0.03	0.62±0.09	0.53±0.15	0.54±0.05
Eosinophils	10^9/L	0.02±0.00	0.04±0.01	0.05±0.01	0.05±0.01
Basophils	10^9/L	0.18±0.03	0.35±0.04	0.33±0.08	0.30±0.02
Red blood cell count	10^12/L	8.55±0.12	8.36±0.17	8.43±0.20	8.24±0.03
Hemoglobin	g/L	14.80±0.21	14.76±0.14	15.02±0.32	14.49±0.08
Hematocrit	%	0.75±0.01	0.74±0.02	0.75±0.02	0.71±0.00
Mean red blood cell volume	fL	88.03±0.74	88.15±1.27	88.51±1.74	86.47±0.81
Mean corpuscular Hb	pg	17.34±0.19	17.70±0.31	17.75±0.22	17.58±0.07
Mean corpuscular Hb concentration	g/L	19.71±0.25	20.16±0.40	20.12±0.40	20.39±0.16
Platelets	10^9/L	1205.61±26.53	1149.19±29.80	1145.28±67.30	1125.36±18.04
Mean platelet cell volume	fL	8.12±0.12	8.46±0.17	8.26±0.19	8.11±0.13

Data are expressed as mean ± SEM.

(b)

	Unit	Treatment for 28 days
		Control	50% methanolic extract of Orthosiphon stamineus
			1250 mg/kg	2500 mg/kg	5000 mg/kg
Female
White blood cell count	10^9/L	7.66±0.96	6.77±0.43	6.31±0.72	7.24±0.35
Neutrophils	10^9/L	1.69±0.32	1.63±0.18	1.47±0.16	1.78±0.18
Lymphocytes	10^9/L	5.35±0.68	4.62±0.52	4.37±0.55	4.26±0.95
Monocytes	10^9/L	0.34±0.08	0.30±0.09	0.31±0.05	0.30±0.03
Eosinophils	10^9/L	0.02±0.01	0.02±0.00	0.02±0.00	0.01±0.00
Basophils	10^9/L	0.27±0.07	0.20±0.04	0.22±0.04	0.19±0.02
Red blood cell count	10^12/L	7.76±0.17	7.79±0.06	7.25±0.36	7.48±0.19
Hemoglobin	g/L	14.16±0.14	14.44±0.12	13.56±0.29	13.64±0.50
Hematocrit	%	0.71±0.01	0.71±0.00	0.67±0.02	0.68±0.01
Mean red blood cell volume	fL	89.47±1.64	90.93±0.52	87.80±1.95	91.09±1.20
Mean corpuscular Hb	pg	18.30±0.25	18.54±0.14	18.01±0.23	18.35±0.56
Mean corpuscular Hb concentration	g/L	20.14±0.18	20.41±0.18	19.85±0.23	20.16±0.56
Platelets	10^9/L	1054.14±57.95	1021.22±14.30	987.46±21.65	1035.83±55.79
Mean platelet cell volume	fL	7.99±0.10	7.78±0.19	7.23±036	7.55±0.10

Data are expressed as mean ± SEM.