Antioxidant and Toxicity Studies of 50% Methanolic Extract of Orthosiphon stamineus Benth

Table 3

Biochemical values of male and female rats treated with 50% methanolic extract of Orthosiphon stamineus for 28 days.

	Unit	Treatment for 28 days
		Control	50% methanolic extract of Orthosiphon stamineus
			1250 mg/kg	2500 mg/kg	5000 mg/kg
Male
Aspartate transaminase (AST)	U/L	122.74±2.19	131.94±3.53	126.79±9.40	121.81±2.45
Alanine aminotransferase (ALT)	U/L	64.51±2.98	62.43±2.59	64.50±3.86	65.22±2.73
Urea	U/L	6.31±0.34	6.65±0.34	6.50±0.40	6.74±0.14
Creatinine	𝜇mol/L	40.56±0.81	39.59±0.30	41.08±1.16	39.33±0.45
Alkaline phosphatase (ALP)	𝜇mol/L	300.56±7.18	309.63±10.08	309.50±11.49	316.86±13.42
Bilirubin	mmol/L	1.80±0.00	1.80±0.00	1.80±0.00	1.80±0.00
Sodium	g/L	142.53±0.36	142.53±0.22	141.96±0.58	142.22±0.31
Potassium	g/L	4.69±0.12	4.64±0.06	4.72±0.07	4.65±0.08
Chlorine	g/L	102.72±0.60	102.71±0.33	103.75±0.28	103.53±0.61
Female
Aspartate transaminase (AST)	U/L	127.83±2.51	127.72±4.98	122.61±10.41	117.28±8.10
Alanine aminotransferase (ALT)	U/L	54.33±2.32	52.17±3.32	53.78±3.41	52.94±1.72
Urea	U/L	7.83±0.46	7.39±0.08	8.00±0.39	7.19±0.29
Creatinine	𝜇mol/L	50.83±2.41	47.72±1.11	47.11±1.27	44.50±0.25
Alkaline phosphatase (ALP)	𝜇mol/L	247.50±8.33	249.72±21.56	250.22±21.23	267.33±9.95
Bilirubin	mmol/L	1.80±0.00	1.80±0.00	1.80±0.00	1.80±0.00
Sodium	g/L	142.83±0.60	142.94±0.20	141.44±0.20	141.11±0.26
Potassium	g/L	4.23±0.14	4.19±0.15	4.04±0.11	4.14±0.15
Chlorine	g/L	102.50±0.62	103.39±0.54	103.17±0.51	103.83±0.46

Data are expressed as mean ± SEM.