Research Article

Comparative Gene Expression Profiling in Human Cumulus Cells according to Ovarian Gonadotropin Treatments

Figure 3

Gonadotropin gene expression associated with in vitro embryo development. (a) and (b) Box-and-whisker plots comparing the expression level of gonadotropin-specific gene in CCs from oocytes that developed into top/good quality embryos ( in the rFSH and in the HP-hMG group) or poor quality embryos ( in the rFSH and in the HP-hMG group) and into good blastocysts ( in the rFSH and in the HP-hMG group) or bad blastocysts ( in the rFSH and in the HP-hMG group). (c) Box-and-whisker plots comparing the expression level of gonadotropin common genes in CCs from oocytes that developed into top/good quality embryos ( CCs) or poor quality embryos ( CCs) and into good blastocysts ( CCs) or bad blastocysts ( CCs). The signal intensity for each gene is shown on the -axis as arbitrary units determined by the Affymetrix GCOS software. *A significant difference with FDR ≤0.05.
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(a) HP-hMG treatment 
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(b) rFSH treatment
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(c) Common to both HP-hMG/rFSH treatments