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BioMed Research International
Volume 2013 (2013), Article ID 358643, 9 pages
Regulation of PKC Autophosphorylation by Calponin in Contractile Vascular Smooth Muscle Tissue
1Department of Health Sciences, Boston University, 635 Commonwealth Avenue, Boston, MA 02215, USA
2Department of Pharmacology, College of Medicine, Dankook University, 119 Dandaero, Chungnam, Cheonan-si 330-714, Republic of Korea
Received 20 August 2013; Revised 10 October 2013; Accepted 24 October 2013
Academic Editor: Goutam Ghosh Choudhury
Copyright © 2013 Hak Rim Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- H. R. Kim, S. Appel, S. Vetterkind, S. S. Gangopadhyay, and K. G. Morgan, “Smooth muscle signalling pathways in health and disease: contractility in health and disease review series,” Journal of Cellular and Molecular Medicine, vol. 12, no. 6A, pp. 2165–2180, 2008.
- K. G. Morgan and S. S. Gangopadhyay, “Signal transduction in smooth muscle: invited review: cross-bridge regulation by thin filament-associated proteins,” Journal of Applied Physiology, vol. 91, no. 2, pp. 953–962, 2001.
- S. S. Gangopadhyay, E. Kengni, S. Appel et al., “Smooth muscle archvillin is an ERK scaffolding protein,” The Journal of Biological Chemistry, vol. 284, no. 26, pp. 17607–17615, 2009.
- A. C. Newton, “Protein kinase C: poised to signal,” The American Journal of Physiology—Endocrinology and Metabolism, vol. 298, no. 3, pp. E395–E402, 2010.
- A. J. M. Cameron and P. J. Parker, “Protein kinase C—a family of protein kinases, allosteric effectors or both?” Advances in Enzyme Regulation, vol. 50, no. 1, pp. 169–177, 2010.
- C. Rosse, M. Linch, S. Kermorgant, A. J. M. Cameron, K. Boeckeler, and P. J. Parker, “PKC and the control of localized signal dynamics,” Nature Reviews Molecular Cell Biology, vol. 11, no. 2, pp. 103–112, 2010.
- R. A. Khalil and K. G. Morgan, “Phenylephrine-induced translocation of protein kinase C and shortening of two types of vascular cells of the ferret,” The Journal of Physiology, vol. 455, pp. 585–599, 1992.
- R. A. Khalil, C. Lajoie, M. S. Resnick, and K. G. Morgan, “Ca2+-independent isoforms of protein kinase C differentially translocate in smooth muscle,” The American Journal of Physiology—Cell Physiology, vol. 263, no. 3, pp. C714–C719, 1992.
- M. P. Walsh, J. E. Andrea, B. G. Allen, O. Clement-Chomienne, E. M. Collins, and K. G. Morgan, “Smooth muscle protein kinase C,” Canadian Journal of Physiology and Pharmacology, vol. 72, no. 11, pp. 1392–1399, 1994.
- M. P. Walsh, A. Horowitz, O. Clément-Chomienne, J. E. Andrea, B. G. Allen, and K. G. Morgan, “Protein Kinase C mediation of Ca2+-independent contractions of vascular smooth muscle,” Biochemistry and Cell Biology, vol. 74, no. 4, pp. 485–502, 1996.
- A. C. Newton, “Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm,” Biochemical Journal, vol. 370, part 2, pp. 361–371, 2003.
- V. O. Rybin, A. Sabri, J. Short, J. C. Braz, J. D. Molkentin, and S. F. Steinberg, “Cross-regulation of novel protein kinase C (PKC) isoform function in cardiomyocytes: role of PKCε in activation loop phosphorylations and PKCδ in hydrophobic motif phosphorylations,” The Journal of Biological Chemistry, vol. 278, no. 16, pp. 14555–14564, 2003.
- A. C. Newton, “Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions,” Chemical Reviews, vol. 101, no. 8, pp. 2353–2364, 2001.
- D. B. Parekh, W. Ziegler, and P. J. Parker, “Multiple pathways control protein kinase C phosphorylation,” The EMBO Journal, vol. 19, no. 4, pp. 496–503, 2000.
- G. Hansra, P. Garcia-Paramio, C. Prevostel, R. D. H. Whelan, F. Bornancin, and P. J. Parker, “Multisite dephosphorylation and desensitization of conventional protein kinase C isotypes,” Biochemical Journal, vol. 342, part 2, pp. 337–344, 1999.
- V. Cenni, H. Döppler, E. D. Sonnenburg, N. Maraldi, A. C. Newton, and A. Toker, “Regulation of novel protein kinase C ε by phosphorylation,” Biochemical Journal, vol. 363, part 3, pp. 537–545, 2002.
- A. Behn-Krappa and A. C. Newton, “The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation,” Current Biology, vol. 9, no. 14, pp. 728–737, 1999.
- K. England and M. G. Rumsby, “Changes in protein kinase C ε phosphorylation status and intracellular localization as 3T3 and 3T6 fibroblasts grow to confluency and quiescence: a role for phosphorylation at ser-729?” Biochemical Journal, vol. 352, part 1, pp. 19–26, 2000.
- V. O. Rybin, J. Guo, A. Sabri, H. Elouardighi, E. Schaefer, and S. F. Steinberg, “Stimulus-specific differences in protein kinase C δ localization and activation mechanisms in cardiomyocytes,” The Journal of Biological Chemistry, vol. 279, no. 18, pp. 19350–19361, 2004.
- A. Horowitz, C. B. Menice, R. Laporte, and K. G. Morgan, “Mechanisms of smooth muscle contraction,” Physiological Reviews, vol. 76, no. 4, pp. 967–1003, 1996.
- B. Leinweber, A. M. Parissenti, C. Gallant et al., “Regulation of protein kinase C by the cytoskeletal protein calponin,” The Journal of Biological Chemistry, vol. 275, no. 51, pp. 40329–40336, 2000.
- H.-D. Je, S. S. Gangopadhyay, T. D. Ashworth, and K. G. Morgan, “Calponin is required for agonist-induced signal transduction—evidence from an antisense approach in ferret smooth muscle,” The Journal of Physiology, vol. 537, part 2, pp. 567–577, 2001.
- C. B. Menice, J. Hulvershorn, L. P. Adam, C.-L. A. Wang, and K. G. Morgan, “Calponin and mitogen-activated protein kinase signaling in differentiated vascular smooth muscle,” The Journal of Biological Chemistry, vol. 272, no. 40, pp. 25157–25161, 1997.
- S. J. Slater, F. J. Taddeo, A. Mazurek et al., “Inhibition of membrane lipid-independent protein kinase Cα activity by phorbol esters, diacylglycerols, and bryostatin-1,” The Journal of Biological Chemistry, vol. 273, no. 36, pp. 23160–23168, 1998.
- J. R. Stewart, N. E. Ward, C. G. Ioannides, and C. A. O'brian, “Resveratrol preferentially inhibits protein kinase C-catalyzed phosphorylation of a cofactor-independent, arginine-rich protein substrate by a novel mechanism,” Biochemistry, vol. 38, no. 40, pp. 13244–13251, 1999.
- Y.-H. Lee, I. Kim, R. Laporte, M. P. Walsh, and K. G. Morgan, “Isozyme-specific inhibitors of protein kinase C translocation: effects on contractility of single permeabilized vascular muscle cells of the ferret,” The Journal of Physiology, vol. 517, part 3, pp. 709–720, 1999.
- T. Kobayashi, K. Taguchi, S. Nemoto, T. Nogami, T. Matsumoto, and K. Kamata, “Activation of the PDK-1/Akt/eNOS pathway involved in aortic endothelial function differs between hyperinsulinemic and insulin-deficient diabetic rats,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 297, no. 5, pp. H1767–H1775, 2009.
- M. P. Scheid, M. Parsons, and J. R. Woodgett, “Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation,” Molecular and Cellular Biology, vol. 25, no. 6, pp. 2347–2363, 2005.
- D. M. Gilligan, R. Sarid, and J. Weese, “Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain,” Blood, vol. 99, no. 7, pp. 2418–2426, 2002.
- S. C. Kiley, K. J. Clark, S. K. Duddy, D. R. Welch, and S. Jaken, “Increased protein kinase Cδ in mammary tumor cells: relationship to transformation and metastatic progression,” Oncogene, vol. 18, no. 48, pp. 6748–6757, 1999.
- B. D. Leinweber, P. C. Leavis, Z. Grabarek, C.-L. A. Wang, and K. G. Morgan, “Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins,” Biochemical Journal, vol. 344, part 1, pp. 117–123, 1999.
- E. Suematsu, M. Resnick, and K. G. Morgan, “Ca2+-independent change in phosphorylation of the myosin light chain during relaxation of ferret aorta by vasodilators,” The Journal of Physiology, vol. 440, pp. 85–93, 1991.
- E. Suematsu, M. Resnick, and K. G. Morgan, “Change of Ca2+ requirement for myosin phosphorylation by prostaglandin F2α,” The American Journal of Physiology—Cell Physiology, vol. 261, no. 2, pp. C253–C258, 1991.
- Y. Shakirova, J. Bonnevier, S. Albinsson et al., “Increased Rho activation and PKC-mediated smooth muscle contractility in the absence of caveolin-1,” The American Journal of Physiology—Cell Physiology, vol. 291, no. 6, pp. C1326–C1335, 2006.
- C. I. Kahwaji, S. Sheibani, S. Han et al., “Evidence that simulated microgravity may alter the vascular nonreceptor tyrosine kinase second messenger pathway,” Proceedings of the Western Pharmacology Society, vol. 43, pp. 75–77, 2000.
- H.-D. Je, C. Gallant, P. C. Leavis, and K. G. Morgan, “Caveolin-1 regulates contractility in differentiated vascular smooth muscle,” The American Journal of Physiology—Heart and Circulatory Physiology, vol. 286, no. 1, pp. H91–H98, 2004.
- C.-L. Chen, Y.-T. Hsieh, and H.-C. Chen, “Phosphorylation of adducin by protein kinase Cδ promotes cell motility,” Journal of Cell Science, vol. 120, no. 7, pp. 1157–1167, 2007.
- C. A. Parker, K. Takahashi, J. X. Tang, T. Tao, and K. G. Morgan, “Cytoskeletal targeting of calponin in differentiated, contractile smooth muscle cells of the ferret,” The Journal of Physiology, vol. 508, no. 1, pp. 187–198, 1998.
- C.-L. A. Wang, “Photocrosslinking of calmodulin and/or actin to chicken gizzard caldesmon,” Biochemical and Biophysical Research Communications, vol. 156, no. 2, pp. 1033–1038, 1988.
- C.-L. A. Wang, L.-W. C. Wang, S. Xu, R. C. Lu, V. Saavedra-Alanis, and J. Bryan, “Localization of the calmodulin- and the actin-binding sites of caldesmon,” The Journal of Biological Chemistry, vol. 266, no. 14, pp. 9166–9172, 1991.
- C.-L. A. Wang, “Caldesmon and smooth-muscle regulation,” Cell Biochemistry and Biophysics, vol. 35, no. 3, pp. 275–288, 2001.
- Y. Liu, C. Graham, A. Li, R. J. Fisher, and S. Shaw, “Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-κB induction,” Biochemical Journal, vol. 361, no. 2, pp. 255–265, 2002.
- S. Cazaubon, F. Bornancin, and P. J. Parker, “Threonine-497 is a critical site for permissive activation of protein kinase Cα,” Biochemical Journal, vol. 301, no. 2, pp. 443–448, 1994.
- F. Bornancin and P. J. Parker, “Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα,” Current Biology, vol. 6, no. 9, pp. 1114–1123, 1996.
- L. Stempka, M. Schnölzer, S. Radke, G. Rincke, F. Marks, and M. Gschwendt, “Requirements of protein kinase Cδ for catalytic function: role of glutamic acid 500 and autophosphorylation on serine 643,” The Journal of Biological Chemistry, vol. 274, no. 13, pp. 8886–8892, 1999.
- S. C. Kiley, K. J. Clark, M. Goodnough, D. R. Welch, and S. Jaken, “Protein kinase C δ involvement in mammary tumor cell metastasis,” Cancer Research, vol. 59, no. 13, pp. 3230–3238, 1999.
- C. Dessy, I. Kim, C. L. Sougnez, R. Laporte, and K. G. Morgan, “A role for MAP kinase in differentiated smooth muscle contraction evoked by α-adrenoceptor stimulation,” The American Journal of Physiology—Cell Physiology, vol. 275, no. 4, pp. C1081–C1086, 1998.
- W. G. Wier and K. G. Morgan, “Alpha1-adrenergic signaling mechanisms in contraction of resistance arteries,” Reviews of Physiology, Biochemistry and Pharmacology, vol. 150, pp. 91–139, 2003.