Identifying the Association Rules between Clinicopathologic Factors and Higher Survival Performance in Operation-Centric Oral Cancer Patients Using the Apriori Algorithm
Table 1
Demographic data of 493 enrolled patients with OSCC.
Characteristics
Survived months
P
5-year survival (%)
P
Total
>36 group
<36 group
Age
0.7786
0.5556
<30
7
3
4
71.4
30~50
228
125
103
77.2
50~70
236
129
107
79.2
>70
22
14
8
63.6
Primary Site
0.7915
0.1957
Lip
36
24
12
86.1
Cheek mucosa
184
103
81
83.2
Gum
42
25
17
71.4
Tongue
175
88
87
72.0
Mouth floor
19
11
8
68.4
Palate
5
3
2
60.0
Retromolar
27
15
12
77.8
Vestibule
2
1
1
100.0
Nonspecific
3
1
2
100.0
Laterality*3
0.3965
0.8612
00
37
22
15
73.0
01
230
123
107
79.1
02
223
123
100
76.7
03
3
3
0
66.7
04
0
0
0
NA
Grade/differentiation
0.1476
0.0006
01
287
156
131
80.1
02
123
60
63
65.0
03
7
5
2
57.1
04
1
1
0
100.0
09
75
49
26
89.3
Regional lymph nodes examined
0.1550
0.1424
<5
285
160
125
80.4
>10
134
65
69
73.1
5~10
73
45
28
74.0
Clinical stage group
0.0749
0.5689
Stage 0
4
0
4
75.0
Stage 1
141
79
62
80.1
Stage 2
73
47
26
71.2
Stage 3
131
69
62
77.1
Stage 4
82
50
32
72.0
Pathologic stage group
0.2540
0.0514
Stage 0
2
2
0
100.0
Stage 1
215
112
103
82.3
Stage 2
92
52
40
75.0
Stage 3
31
15
16
74.2
Stage 4
58
24
34
67.2
Clinical tumor size
0.3967
0.0004
<2 cm
162
100
62
87.0
2~4 cm
244
134
110
71.3
>4 cm
33
19
14
66.7
Pathology tumor size
0.4417
0.0141
<2 cm
197
114
83
81.7
2~4 cm
183
94
89
69.4
>4 cm
25
14
11
72.0
OP group*4
<0.0001
<0.0001
01
385
238
147
81.6
02
27
14
13
66.7
03
81
19
62
61.7
value for the comparison of the survival between >36 and <36 months groups. value for 5-year survival among the items of the same characteristics group. 0: unknown primary site or the shape of the organ is not paired; 1: the primary site is originated from the right side; 2: the primary site is originated from the left side; 3: only one side is invaded but it is not clear which side (R't or L't) it is originated from; 4: both sides are invaded but the origin of the primary site is not clear and the chart record describes only one primary site. OP group for 01: OP only; 02: OP→IA; 03: OP→CT, OP→CT + IV, OP→CT→RT, OP→IA→RT, OP→IV,OP→IV→RT, OP→RT, OP→RT + CT,OP→RT + IV, OP→RT→CT, OP→RT→IA, OP→RT→IV. Symbols: OP: operation; IA: intraarterial chemotherapy; CT: oral chemotherapy; IV: intravenous chemotherapy; RT: radiotherapy; →: then.