Clinical Study

Dietary Intake as a Link between Obesity, Systemic Inflammation, and the Assumption of Multiple Cardiovascular and Antidiabetic Drugs in Renal Transplant Recipients

Table 1

Demographic, anthropometric, and body composition data and the pharmacological of treatment the three groups of kidney transplant recipients divided according to BMI.

NW OW
OB

Male/female36/1420/812/6
Age, years51.5 ± 10.448.7 ± 8.550.3 ± 10.1
Transplant time, years7.8 ± 5.15.6 ± 4.37.9 ± 5.5
Pretransplant BW, Kg58.2 ± 12.066.6 ± 9.4*74.4 ± 12.1*
Pretransplant BMI, Kg/m²21.6 ± 2.924.2 ± 2.3*28.2 ± 3.2*
BW, Kg60.5 ± 9.374.5 ± 36.7*87.7 ± 11.7*
BMI, Kg/m²22.5 ± 2.027.2 ± 1.3*33.3 ± 3.2*
ΔBW, % of pre-transplant BW5.6 ± 11.813.0 ± 11.5*19.0 ± 12.6*
TBW, % BW59.4 ± 6.354.8 ± 4.9*47.9 ± 3.8*
ECW, % TBW45.6 ± 3.943.9 ± 4.844.2 ± 4.4
FM, % BW19.9 ± 8.725.5 ± 6.4*35.6 ± 6.7*
FFM, % BW80.0 ± 8.774.4 ± 6.4*64.4 ± 6.7*
BCM, Kg25.4 ± 5.830.0 ± 6.1*29.5 ± 5.7*
TBW/FFM0.74 ± 0.020.73 ± 0.010.74 ± 0.02
Systolic blood pressure (mmHg)126 ± 11130 ± 14128 ± 8
Diastolic blood pressure (mmHg)80 ± 781 ± 380 ± 5
Cumulative corticosteroid dose (g)10.8 ± 8.58.1 ± 6.48.9 ± 8.1
Oral antidiabetic drugs/Insulin therapy (%)0/414/00/22
Lipid-lowering therapy (%)527178
Antihypertensive therapy (%)100100100

BW: body weight; BMI: body mass index; FM: fat mass; FFM: fat-free mass; TBW: total body water; ECW: extracellular water; BCM: body cell mass.
* versus NW; versus OW; ANOVA (with Bonferroni’s posttest).