SNP rs2073618 of the Osteoprotegerin Gene Is Associated with Diabetic Retinopathy in Slovenian Patients with Type 2 Diabetes

Table 2

Distribution of rs2073618 and rs3134069 genotypes and alleles in patients with diabetic retinopathy (cases) and in those without diabetic retinopathy (controls).

	Cases (280)	Controls (365)	P value
rs2073618 (c.9C>G)
CC	70 (25)	66 (18.1)
CG	132 (47.1)	164 (44.9)	0.02
GG	78 (27.9)	135 (37)
C allele (%)	272 (48.6)	296 (40.5)
G allele (%)	288 (51.4)	434 (59.5)	0.004
rs3134069 (g.119964988A>C)
CC	6 (2.2)	1 (0.3)
AC	48 (17.1)	36 (9.9)	0.001
AA	226 (80.7)	328 (89.8)
C allele (%)	60 (10.7)	38 (5.2)
A allele (%)	500 (89.3)	692 (94.8)	0.0002

Bold indicates statistically significant results.