Table 1: Omega-3 effects on bladder cancer chemoprevention: macroscopic (quantitative) and microscopic (qualitative) evaluation of urothelial lesions.

Macroscopy (quantitative) & microscopy (qualitative)Control
( )
Omega-3
( )
BBN
( )
Omega-3 + BBN
( )

Tumor number
 Rats with tumor [% ( )]0065.0 (13 in 20)62.5 (5 in 8)
 Tumors/rat [mean ( )]00 (16 in 13) (6 in 5)
Tumor volume
 Mean/rat [mm3 ( )]00 (in 13) (in 5)
 Mean/tumor [mm3 ( )]00 (in 16) (in 6)

Preneoplasic lesions [% ( )]
 Hyperplasia00100 (20 in 20)87.5 (7 in 8)
 High-grade dysplasia00100 (20 in 20)0 (0 in 8)
Neoplasic lesions [% ( )]
 Papillary tumor00100 (13 in 13)100 (5 in 5)
 Infiltrative tumor0015 (2 in 13)0 (0 in 5)
 Carcinoma in situ 0031 (4 in 13)0 (0 in 5)