No Immunogenicity of IPS Cells in Syngeneic Host Studied by In Vivo Injection and 3D Scaffold Experiments
Figure 3
Growth of MEF iPSCs in scaffold transplanted in syngeneic mice and rejection of iPSCs in scaffold transplanted in allogeneic mice. MEF iPSCs (1 × 105) were cultured in scaffolds for 2 weeks and transplanted into C57BL/6 mice or BALB/c mice. After different time periods the scaffolds were removed from the mice and frozen in OCT. Hematoxylin and Eosin staining of the scaffolds operated at day 6, 20, and 49 from the syngeneic and allogeneic host is shown.
