Improvements in the Quantitative Assessment of Cerebral Blood Volume and Flow with the Removal of Vessel Voxels from MR Perfusion Images

Table 1

Previously reported literature values of the CBV and CBF of normal gray and white matter measured using various imaging modalities.

Modality	CBV (mL/100 g)		CBF (mL/100 g/min)
	GM	WM	GM	WM	Reference
PET	4.5	2.7	47	20	[8]
PET	3.7	1.3	45	17	[9]
PET			51	38	[20]
CT, VPE	3.9–5.3		51–71		[21]
CT, VPE			53	30	[20]
CT, VPE			42	13	[15]
MR	8.0	4.2	70	34	[3]
MR	6.8	3.8	69	36	[7]
MR	6.0	2.4	59	18	[9]
MR, VOF	9.1	4.6	64	21	[8]
MR, VOF			68	27	[14]
MR, VOF			57	25	[15]
MR, SS	3.7	1.8	57	18	[22]

CT: perfusion CT, MR: dynamic-susceptibility-contrast perfusion MRI, PET: H₂¹⁵O positron emission tomography, GM: normal gray matter, WM: normal white matter, VPE: vascular pixel elimination, VOF: partial volume correction using a venous output function, and SS: CBV and CBF scaling using steady-state CBV images.