Relationship between Circulating BAFF Serum Levels with Proliferating Markers in Patients with Multiple Myeloma

Table 3

Mean ± SD values of B-cell activating factor (BAFF), interleukin-6, -10, and -15 (IL-6, -10, and -15), C-reactive protein (CRP), beta-2 microglobulin (B2M), Ki-67 proliferation index (Ki-67 PI), and plasma cell infiltration before and after effective treatment (𝑃<0.003 for CRP, 𝑃<0.007 for B2M, and 𝑃<0.001 for other cases).

	Pretreatment	Posttreatment
BAFF (pg/mL)	889.2 ± 681.4	303.4 ± 163.5
IL-6 (pg/mL)	7.5 ± 5.2	2.6 ± 1.3
IL-10 (pg/mL)	174.6 ± 77.0	131.3 ± 21.3
IL-15 (pg/mL)	9.5 ± 4.9	6.6 ± 1.8
CRR (mg/dL)	0.95 ± 0.66	0.51 ± 0.20
B2M (mg/L)	3.65 ± 3.19	2.06 ± 0.77
Ki-67 PI (%)	9.3 ± 7.5	2.7 ± 2.4
Infiltration (%)	39.4 ± 19.3	6.7 ± 5.1