In Vivo Biocompatibility of PLGA-Polyhexylthiophene Nanofiber Scaffolds in a Rat Model

Figure 2

Micrographs of hematoxylin-eosin-stained tissue implanted with PLGA random nanofibers at (a) 2 weeks, (b) 4 weeks, and (c) 8 weeks; with PLGA-undoped PHT random fibers at (d) 2 weeks, (e) 4 weeks, and (f) 8 weeks; with PLGA-doped PHT random fibers at (g) 2 weeks, (h) 4 weeks, and (i) 8 weeks; and with PLGA-doped PHT aligned nanofibers at (j) 2 weeks, (k) 4 weeks, and (l) 8 weeks. C: collagen; L: lymphocytes; M: macrophages; F: fibroblast; G: giant cell; and arrows indicate implant sites.

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