Table 3: Inflammatory response to random PLGA, random PLGA-undoped PHT, random PLGA-doped PHT, and aligned PLGA-doped PHT nanofibers after 2, 4, and 8 weeks of implantation. Mod: moderate.

PLGA (R)PLGA-undoped PHT (R)PLGA-doped PHT (R)PLGA-doped PHT (A)
2 W4 W8 W2 W4 W8 W2 W4 W8 W2 W4 W8 W

Lymphocytes+++++++++++++++++++++++++++++++++++++++++
PMNs++
Giant cells++++++++++++++++
Plasma cells+++
Tissue responseMildMod Mild Mod Mod Mod Mod Mod MildMod Mild Mild