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BioMed Research International
Volume 2013 (2013), Article ID 394316, 9 pages
Interleukin-13 +1923C/T Polymorphism Is Associated with Asthma Risk: A Meta-Analysis
1Department of Intensive Care Medicine, No. 411 Hospital of PLA, Shanghai 200080, China
2Department of Respiratory Disease, Shanghai Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China
3Department of Respiratory Disease, Fuzhou Military General Hospital, Fuzhou, Fujian 350025, China
Received 12 March 2013; Accepted 22 May 2013
Academic Editor: Koji Kawakami
Copyright © 2013 Yongan Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- M. Masoli, D. Fabian, S. Holt, and R. Beasley, “The global burden of asthma: executive summary of the GINA dissemination committee report,” Allergy, vol. 59, no. 5, pp. 469–478, 2004.
- D. L. Duffy, N. G. Martin, D. Battistutta, J. L. Hopper, and J. D. Mathews, “Genetics of asthma and hay fever in Australian twins,” The American Review of Respiratory Disease, vol. 142, no. 6, pp. 1351–1358, 1990.
- M. Wills-Karp, J. Luyimbazi, X. Xu et al., “Interleukin-13: central mediator of allergic asthma,” Science, vol. 282, no. 5397, pp. 2258–2261, 1998.
- G. Grünig, M. Warnock, A. E. Wakil et al., “Requirement for IL-13 independently of IL-4 in experimental asthma,” Science, vol. 282, no. 5397, pp. 2261–2263, 1998.
- S. K. Huang, H. Q. Xiao, J. Kleine-Tebbe et al., “IL-13 expression at the sites of allergen challenge in patients with asthma,” Journal of Immunology, vol. 155, no. 5, pp. 2688–2694, 1995.
- J. Prieto, C. Lensmar, A. Roquet et al., “Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations,” Respiratory Medicine, vol. 94, no. 8, pp. 806–814, 2000.
- S. K. Saha, M. A. Berry, D. Parker et al., “Increased sputum and bronchial biopsy IL-13 expression in severe asthma,” Journal of Allergy and Clinical Immunology, vol. 121, no. 3, pp. 685–691, 2008.
- D. Vercelli, “Discovering susceptibility genes for asthma and allergy,” Nature Reviews Immunology, vol. 8, no. 3, pp. 169–182, 2008.
- H. Yang, H. Dong, Y. Dai, and Y. Zheng, “Association of interleukin-13 C-1112T and G+2044A polymorphisms with asthma: a meta-analysis,” Respirology, vol. 16, no. 7, pp. 1127–1135, 2011.
- L. Cui, J. Jia, C. Ma et al., “IL-13 polymorphisms contribute to the risk of asthma: a meta-analysis,” Clinical Biochemistry, vol. 45, no. 4-5, pp. 285–288, 2012.
- H. Hákonarson, U. S. Bjornsdottir, E. Ostermann et al., “Allelic frequencies and patterns of single-nucleotide polymorphisms in candidate genes for asthma and atopy in Iceland,” The American Journal of Respiratory and Critical Care Medicine, vol. 164, no. 11, pp. 2036–2044, 2001.
- J. Donfack, D. H. Schneider, Z. Tan et al., “Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy,” Respiratory Research, vol. 6, pp. 145–157, 2005.
- M. F. Moffatt, I. G. Gut, F. Demenais et al., “A large-scale, consortium-based genomewide association study of asthma,” The New England Journal of Medicine, vol. 363, no. 13, pp. 1211–1221, 2010.
- X. Li, T. D. Howard, S. L. Zheng et al., “Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions,” Journal of Allergy and Clinical Immunology, vol. 125, no. 2, pp. 328.e11–335.e11, 2010.
- A. Thakkinstian, M. McEvoy, C. Minelli et al., “Systematic review and meta-analysis of the association between β2-adrenoceptor polymorphisms and asthma: a HuGE review,” The American Journal of Epidemiology, vol. 162, no. 3, pp. 201–211, 2005.
- A. Thakkinstian, P. McElduff, C. D'Este, D. Duffy, and J. Attia, “A method for meta-analysis of molecular association studies,” Statistics in Medicine, vol. 24, no. 9, pp. 1291–1306, 2005.
- W. Nie, Z. Fang, B. Li, and Q. Xiu, “Interleukin-10 promoter polymorphisms and asthma risk: a meta-analysis,” Cytokine, vol. 60, no. 3, pp. 849–855, 2012.
- W. Nie, J. Chen, and Q. Xiu, “Cytotoxic T-lymphocyte associated antigen 4 polymorphisms and asthma risk: a meta-analysis,” PLoS ONE, vol. 7, no. 7, Article ID e42062, 2012.
- M. Egger, G. D. Smith, M. Schneider, and C. Minder, “Bias in meta-analysis detected by a simple, graphical test,” The British Medical Journal, vol. 315, no. 7109, pp. 629–634, 1997.
- J. Liu, B. Wu, H. Cheng, et al., “Correlation between +1923C/T polymorphism in IL-13 gene and asthma and its impact on total plasma IgE levels,” Journal of Guangdong Medical College, vol. 22, pp. 211–214, 2004.
- N. C. Battle, S. Choudhry, H. Tsai et al., “Ethnicity-specific gene-gene interaction between IL-13 and IL-4Rα among African Americans with asthma,” The American Journal of Respiratory and Critical Care Medicine, vol. 175, no. 9, pp. 881–887, 2007.
- D. Daley, M. Lemire, L. Akhabir et al., “Analyses of associations with asthma in four asthma population samples from Canada and Australia,” Human Genetics, vol. 125, no. 4, pp. 445–459, 2009.
- X. Wu, Y. Li, Q. Chen et al., “Association and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle China,” Journal of Asthma, vol. 47, no. 3, pp. 238–244, 2010.
- E. Noguchi, H. Sakamoto, T. Hirota et al., “Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations,” PLoS Genetics, vol. 7, no. 7, Article ID e1002170, 2011.
- D. Yoon, H. J. Ban, Y. J. Kim et al., “Replication of genome-wide association studies on asthma and allergic diseases in Korean adult population,” BMB Reports, vol. 45, no. 5, pp. 305–310, 2012.
- D. M. Walter, J. J. McIntire, G. Berry et al., “Critical role for IL-13 in the development of allergen-induced airway hyperreactivity,” Journal of Immunology, vol. 167, no. 8, pp. 4668–4675, 2001.
- G. Yang, A. Volk, T. Petley et al., “Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling,” Cytokine, vol. 28, no. 6, pp. 224–232, 2004.
- M. Granada, J. B. Wilk, M. Tuzova et al., “A genome-wide association study of plasma total IgE concentrations in the Framingham heart study,” Journal of Allergy and Clinical Immunology, vol. 129, no. 3, pp. 840.e21–845.e21, 2012.
- L. M. Maier, J. M. M. Howson, N. Walker et al., “Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes,” Journal of Allergy and Clinical Immunology, vol. 117, no. 6, pp. 1306–1313, 2006.
- A. Sadeghnejad, W. Karmaus, S. H. Arshad, and S. Ewart, “IL13 gene polymorphism association with cord serum immunoglobulin E,” Pediatric Allergy and Immunology, vol. 18, no. 4, pp. 288–292, 2007.
- A. Sadeghnejad, W. Karmaus, S. H. Arshad, R. Kurukulaaratchy, M. Huebner, and S. Ewart, “IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study,” Respiratory Research, vol. 9, pp. 2–12, 2008.
- W. Nie, B. Li, and Q. Xiu, “The -675 4g/5g polymorphism in plasminogen activator inhibitor-1 gene is associated with risk of asthma: a meta-analysis,” PLoS ONE, vol. 7, no. 3, Article ID e34385, 2012.