Table 2: Comparison of clinicopathological characteristics between intestinal type GC cases of sporadic and familial GCs.

Sporadic GCFamilial GC
( )( ) value
(%) (%)

Age (years) <0.001
Gender (M/F)124/2924/170.006
Tumor maximal size (cm) <0.001
Gross appearance
 Well-defined64 (41.8)21 (51.2)
 Ill-defined89 (58.2)20 (48.8)0.293
Lymphovascular invasion
 Absent/present23/13019/22<0.001
Stromal reaction type
 Medullary16 (10.5)14 (34.2)
 Intermediate104 (68)19 (46.3)
 Scirrhous33 (21.5)8 (19.5)0.001
Pathological T category
 T1/T2/T3/T415/22/36/8016/2/7/16<0.001
Pathological N category
 N0/N1/N2/N339/25/29/6019/5/3/140.047
Pathological TNM stage
 Stage I24 (15.7)16 (39)
 Stage II33 (21.6)7 (17.1)
 Stage III46 (30.1)8 (19.5)
 Stage IV50 (32.7)10 (24.4)0.012
MSI status
 MSI-L/S128 (83.7)35 (85.4)
 MSI-H25 (16.3)6 (14.6)1.000
IHC stain for MMR protein
 Normal143 (93.5)38 (92.7)
 Abnormal10 (6.5)3 (7.3)1.000