BioMed Research International

Research Article

In Vitro Cytotoxicity and In Vivo Acute and Chronic Toxicity of Xanthii Fructus and Its Processed Product

Figure 4

Comparison of microscopic morphology in kidney (a, b, and c), liver (d, e, and f), heart (g, h, and i), and lung (j, k, and l) tissue between control group (a and d), high dosage XF group (b and e), and high dosage PXF group (c and f). Original magnification ×400.
403491.fig.004a
(a) Normal group
403491.fig.004b
(b) Intracellular edema, hemorrhage, and loosening of cytoplasm were observed in dead mice kidney tissue of high dosage XF group
403491.fig.004c
(c) Little hemorrhage was observed in dead mice kidney tissue of high dosage PXF group
403491.fig.004d
(d) Normal group
403491.fig.004e
(e) Light intracellular edema and hemorrhage were observed in dead mice liver tissue of high dosage XF group
403491.fig.004f
(f) Light intracellular edema was observed in dead mice liver tissue of high dosage PXF group
403491.fig.004g
(g) Normal group
403491.fig.004h
(h) Myocardial cell cytoplasm osteoporosis, intracellular edema, hemorrhage, and fatty degeneration were observed in dead mice heart tissue of high dosage XF group
403491.fig.004i
(i) Myocardial cell cytoplasm osteoporosis, little intracellular edema, and hemorrhage were observed in dead mice heart tissue of high dosage PXF group
403491.fig.004j
(j) Normal group
403491.fig.004k
(k) Light intracellular edema, thickening alveolar wall, and severe bronchial hemorrhage were observed in dead mice lung tissue of high dosage XF group
403491.fig.004l
(l) Light intracellular edema and little bronchial hemorrhage were observed in dead mice lung tissue of high dosage PXF group