Research Article
In Vitro Cytotoxicity and In Vivo Acute and Chronic Toxicity of Xanthii Fructus and Its Processed Product
Table 7
Kidney and liver pathological damage occurrence rates (%) in chronic toxicity assays.
| Groups | I | II | III | IV | V | VI | VII |
| Kidney | | | | | | | | Tubular edema | 0 | 25 | 50 | 0 | 33 | 0 | 50 | Renal interstitial Inflammatory infiltration | 0 | 50 | 75 | 0 | 33 | 0 | 25 | Renal tubular exudation | 0 | 50 | 75 | 50 | 33 | 0 | 25 | Tubular necrosis | 0 | 25 | 50 | 0 | 33 | 0 | 25 | Fibrosis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | Liver | | | | | | | | Liver cell edema | 0 | 25 | 0 | 25 | 50 | 75 | 25 | Spotty necrosis | 0 | 75 | 100 | 0 | 50 | 0 | 25 | Focal necrosis | 0 | 25 | 50 | 0 | 25 | 0 | 0 | Inflammation | 0 | 0 | 50 | 0 | 25 | 0 | 0 | Fibrosis | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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