Table 2: The risk of asbestosis for MnSOD, ECSOD, CAT, GSTT1, GSTM1, GSTP1, and iNOS genotypes*.

GenotypeOR (95% CI)
UnadjustedAdjusted by
GenderAgeSmoking (ever/never)Cumulative exposure

MnSOD −9Ala/Ala versus Ala/Val + Val/Val1.50 (1.01–2.24)1.49 (1.00–2.23)1.46 (0.97–2.19)1.49 (1.00–2.23)1.48 (0.96–2.28)
ECSOD Arg/Gly versus Arg/Arg1.63 (0.62–4.27)1.61 (0.61–4.22)1.49 (0.56–3.96)1.65 (0.63–4.32)2.07 (0.72–5.94)
CAT −262 TT versus CT + CC1.36 (0.70–2.62)1.34 (0.70–2.60)1.31 (0.67–2.57)1.37 (0.71–2.66)1.91 (0.93–3.91)
GSTM1-null versus present1.01 (0.71–1.43)1.00 (0.70–1.42)0.94 (0.66–1.35)0.99 (0.70–1.41)0.97 (0.67–1.42)
GSTT1-null versus present0.61 (0.40–0.94)0.62 (0.40–0.94)0.63 (0.40–0.97)0.63 (0.41–0.97)0.60 (0.38–0.96)
GSTP1 105Ile/Ile versus Ile/Val + Val/Val1.52 (1.08–2.15)1.53 (0.60–1.28)1.49 (1.04–2.11)1.54 (1.08–2.18)1.41 (0.97–2.05)
GSTP1 114Ala/Ala versus Ala/Val + Val/Val0.97 (0.64–1.48)0.97 (0.64–1.48)0.99 (0.65–1.53)0.94 (0.62–1.44)0.86 (0.55–1.36)
GSTP1 high versus intermediate + low conjugation capacity1.49 (1.06–2.10)1.50 (1.06–2.11)1.45 (1.03–1.07)1.50 (1.06–2.13)1.36 (0.94–1.98)
iNOS LL versus SL + SS1.20 (0.85–1.69)1.20 (0.85–1.70)1.19 (0.84–1.69)1.17 (0.83–1.66)1.19 (0.82–1.73)

The table summarizes the results from our previous studies.