Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobins and Annexin A1
Figure 1
Lung CCSP protein levels. Western blot analyses were performed on lung homogenates prepared from ((a) and (d)) E19 and d0; ((b) and (e)) 1 d, 3 d, 7 d, and 14 d; and ((c) and (f)) 28 d animals as described in Section 2. Animals were exposed to room air or 85% O2 as indicated. All data were normalized to d1 room air. Data (mean ± SEM, −9) were analyzed by Mann-Whitney U test or two-way ANOVA followed by Tukey’s multiple comparison test post hoc. Analyses indicated an independent effect of exposure on CCSP levels. (* versus d1 RA).
