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BioMed Research International
Volume 2013 (2013), Article ID 408485, 10 pages
http://dx.doi.org/10.1155/2013/408485
Research Article

Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobins and Annexin A1

1Nationwide Children’s Hospital, The Ohio State University College of Medicine, Columbus, OH 43205, USA
2The Research Institute at Nationwide Children’s Hospital, 575 Children’s Crossroad, Columbus, OH 43215, USA
3Baylor College of Medicine, Houston, TX 77030, USA

Received 4 April 2013; Revised 27 August 2013; Accepted 28 August 2013

Academic Editor: Hartmut Jaeschke

Copyright © 2013 Thomas M. Raffay et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1 contains lung histologic analyses from newborn mice exposed to room air or hyperoxia for 14 days. Separate groups of mice were exposed to room air for 28 days or was exposed to 14 days of hyperoxia followed by exposure to room air for an additional 14 days. Formal morphometric analyses from 28 d mice are also shown.

Supplementary Figure 2 contains immunohistochemical analyses for Clara cell secretory protein (CCSP) in lung sections obtained from newborn mice exposed to room air for 28 days or exposed to hyperoxia for 14 days followed exposure to room air for an additional 14 days.

  1. Supplementary Figures