Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats

<table>Age-related differences in specific activities of biotransformation enzymes with oxidizing activity in rat liver. The white column represents young (6-week-old) rats, and the hatched column indicates old (21-month-old) rats. The activities of individual CYP isoforms were normalized to the total CYP content. Data of each age group represent the mean ± SD (six animals per age group) (*data with <svg height="11.375" id="M8" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, Student’s <i>t</i>-test). CYP = cytochrome P450; FMO = flavine monooxygenase.</table>

BioMed Research International

fig1

Figure 1

Figure 1: Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats 