Reduced T Cell Receptor Excision Circle Levels in the Colonic Mucosa of Microscopic Colitis Patients Indicate Local Proliferation rather than Homing of Peripheral Lymphocytes to the Inflamed Mucosa

Figure 2

Levels of T cell receptor excision circles (TRECs) in colonic mucosa of patients with collagenous colitis (CC), CC-histopathological remission (CC-HR), lymphocytic colitis (LC), LC-histopathological remission (LC-HR), noninflamed diarrhoea patients and controls. The relative expression was calculated by the 2^(−ΔΔCt) method. Each symbol represents data from one individual. One symbol with the circle in LC-HR group represents a statistical outlier, and was excluded from the statistical calculations. Controls, 𝑛=10; CC, 𝑛=8; CC-HR, 𝑛=3; LC, 𝑛=5; LC-HR, 𝑛=6; and noninflamed diarrhoea, 𝑛=17.