Clinical Study

Effectiveness of Green Tea in a Randomized Human Cohort: Relevance to Diabetes and Its Complications

Table 4

Characteristics of female participants ( ) at baseline, after 14-week intervention period, and after 2-week washout period.

VariablesFemale green tea groupFemale control group
n BaselineWeek 14Washoutn BaselineWeek 14Washout

Age (year)32 28
Weight (kg)32 28
BMI (kg/m2)31 (0.6) (0.2)28 (0.1) (0.4)
Waist-hip ratio31 (0.0) (2.0)*27 (1.8)* (2.4)*
MAPa (mmHg)31 (−1.2) (−0.2)27 (−2.6)* (−2.4)
Glucose (mg/dL)32 (0.5) (−1.8)28 (4.1)* (−0.3)
HbA1c (%)306.10 5.90–6.50 5.95 [5.80–6.30]6.10 [5.90–6.40]256.00 [5.78–6.10]5.90 [5.80–6.20]6.00 [5.88–6.30]*
Cholesterol (mg/dL)31 (−4.8) (−0.8)28 (−8.1)* (−5.5)*
Triglycerides (mg/dL)31 (−6.4) (5.4)25 (9.0) (10.1)
LDL (mg/dL)30 (−7.9)* (−1.5)27 (−13.7)* (−4.7)
HDL (mg/dL)31 (−3.8)* (−1.6)28 (−5.2)* (−5.6)*
LDL/HDL29 (−5.5) (−0.7)27 (−11.6) (−3.2)
Ferritin (ng/dL)29 (11.7) (14.8)26 (−6.3) (6.2)
Albumin (g/dL)29 (−0.9) (1.3)25 (−2.3)* (−1.4)
Serum creatinine (mg/dL)310.90 [0.83–1.00]0.90 [0.80–1.00]0.80 [0.80–0.98]*280.90 [0.80–0.95]0.90 [0.80–0.90]0.80 [0.80–0.90]*
Urinary creatinine (mg/dL)30 (18.2) (−11.7)23 (9.7) (−13.2)
Urea (mg/dL)32 (1.4) (−5.4)27 (−5.2) (−7.0)
eGFRb (mL/min per 1.73 m2)28 (3.7) (6.3)*27 (3.3) (9.1)*
ASTc (IU/L)31 (0.7) (−3.8)27 (0.7) (3.6)
ALTd (IU/L)29 (−13.0)* (−10.0)*26 (−6.9) (−6.4)
TASe (mmol/L)29 (11.9)* (19.6)*24 (8.3)*# (21.1)*
Human sera HT50 (minutes)31 (5.1)* (3.6)*26 (−0.9) (−0.2)

Parametric variables are expressed as mean ± standard deviation, whereas nonparametric variables are expressed as median [interquartile range]. Percentage change relative to baseline means are indicated in round brackets. *Mean or median value is significantly different from that of baseline ( ) (compare within row and within group). #Mean or median value is significantly different from that of week 14 ( ) (compare within row and between group). aMean arterial pressure; bestimated glomerular filtration rate; caminotransferase aspartate; daminotransferase alanine; etotal antioxidant status.