Polyisoprenylated Methylated Protein Methyl Esterase Is Both Sensitive to Curcumin and Overexpressed in Colorectal Cancer: Implications for Chemoprevention and Treatment
Figure 1
Inhibition of PMPMEase by curcumin. (a) Purified PMPMEase (5 μg) was incubated with RD-PNB in the presence of varying concentrations of the indicated concentrations of curcumin for 1 h. The reactions were stopped with methanol and analyzed for the residual PMPMEase activity as described in the methods section. (b) The results are expressed as the means relative to the controls (±SEM, ).
